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首页> 外文期刊>The journal of asthma >Progressive epidural lipomatosis with steroid use in severe refractory asthma.
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Progressive epidural lipomatosis with steroid use in severe refractory asthma.

机译:在严重难治性哮喘中使用类固醇进行性硬膜外脂肪瘤病。

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BACKGROUND: Long-term immunosuppression with oral corticosteroids is frequently used to treat inflammatory diseases of the lung and is advocated in the management of some patients with asthma. METHODS: The authors describe the case of a 35-year-old man with severe refractory asthma who developed a slowly progressive thoracic spinal cord syndrome. RESULTS: Spinal imaging demonstrated the presence of spinal epidural lipomatosis, a rare complication of prolonged corticosteroid therapy, which is characterized by overgrowth of fat in the epidural space and neuronal compression. CONCLUSIONS: Spinal epidural lipomatosis should be considered in patients receiving long-term corticosteroid therapy who develop symptoms and signs suggestive of spinal cord compression.
机译:背景:口服糖皮质激素的长期免疫抑制常用于治疗肺部炎症,并在某些哮喘患者的治疗中得到提倡。方法:作者描述了一个患有严重难治性哮喘的35岁男子的病例,该男子发展为缓慢进行性胸椎脊髓综合征。结果:脊柱成像显示存在硬膜外脂肪瘤病,这是长期使用皮质类固醇激素治疗的罕见并发症,其特征是硬膜外间隙脂肪过度生长和神经元受压。结论:长期接受皮质类固醇激素治疗的患者,如果出现症状和体征提示脊髓受压,应考虑进行硬脊膜外脂肪瘤病治疗。

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