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首页> 外文期刊>Journal of Bioinformatics and Computational Biology >Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior
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Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior

机译:非均匀生物膜力学行为的多层复合力学建模

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摘要

Experiments showed that bacterial biofilms are heterogeneous, for example, the density, the diffusion coefficient, and mechanical properties of the biofilm are different along the biofilm thickness. In this paper, we establish a multi-layer composite model to describe the biofilm mechanical inhomogeneity based on unified multiple-component cellular automaton (UMCCA) model. By using our model, we develop finite element simulation procedure for biofilm tension experiment. The failure limit and biofilm extension displacement obtained from our model agree well with experimental measurements. This method provides an alternative theory to study the mechanical inhomogeneity in biological materials.
机译:实验表明细菌生物膜是异质的,例如,生物膜的密度,扩散系数和机械性能沿生物膜厚度不同。在本文中,我们建立了一个多层复合模型来描述基于统一的多组分细胞自动机(UMCCA)模型的生物膜机械不均匀性。通过使用我们的模型,我们为生物膜张力实验开发了有限元模拟程序。从我们的模型获得的破坏极限和生物膜延伸位移与实验测量结果非常吻合。该方法提供了另一种理论来研究生物材料中的机械不均匀性。

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