Microarrays in biology and medicine.

Choudhuri S

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Microarrays in biology and medicine.

机译：生物和医学中的微阵列。

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The remarkable speed with which biotechnology has become critical to the practice of life sciences owes much to a series of technological revolutions. Microarray is the latest invention in this ongoing technological revolution. This technology holds the promise to revolutionize the future of biology and medicine unlike any other technology that preceded it. Development of microarray technology has significantly changed the way questions about diseases and/or biological phenomena are addressed. This is because microarrays facilitate monitoring the expression of thousands of genes or proteins in a single experiment. This enormous power of microarrays has enabled scientists to monitor thousands of genes and their products in a given living organism in one experiment, and to understand how these genes function in an orchestrated manner. Obtaining such a global view of life at the molecular level was impossible using conventional molecular biological techniques. However, despite all the progress made in developing this technology, microarray is yet to reach a point where all data are obtained, analyzed, and shared in a standardized fashion. The present article is a brief overview of microarray technologies and their applications with an emphasis on DNA microarray. (c) 2004 Wiley Periodicals, Inc. J Biochem Mol Toxicol 18:171-179, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20023.

机译：生物技术对生命科学实践至关重要的惊人速度，很大程度上归因于一系列技术革命。微阵列是这一正在进行的技术革命中的最新发明。这项技术有望改变生物学和医学的未来，这与之前的其他任何技术都不一样。微阵列技术的发展已大大改变了有关疾病和/或生物现象的问题的解决方式。这是因为微阵列可在单个实验中促进监测数千种基因或蛋白质的表达。微阵列的巨大功能使科学家能够通过一项实验监控给定生物中的数千种基因及其产物，并了解这些基因如何以协调的方式发挥作用。使用常规的分子生物学技术不可能在分子水平上获得如此全面的生命观。但是，尽管在开发该技术方面取得了所有进展，但微阵列仍未达到以标准化方式获取，分析和共享所有数据的地步。本文是对微阵列技术及其应用的简要概述，重点是DNA微阵列。（c）2004 Wiley Periodicals，Inc. J Biochem Mol Toxicol 18：171-179，2004;在线发布于Wiley InterScience（www.interscience.wiley.com）。 DOI 10.1002 / jbt.20023。

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《Journal of biochemical and molecular toxicology》 |2004年第4期|共1页
作者
Choudhuri S;
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正文语种 eng
中图分类药学;
关键词
Medicine; Biology; experiment; livin; g lt; 3gt; 医学; 生物学;

机译：Medicine;Biology;experiment;livin;g 3;医学;生物学;

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Microarrays in biology and medicine.

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