Analysis of hydrophobic and charged patches and influence of medium- and long-range interactions in molecular chaperones.

Kumarevel TS; Gromiha MM; Ponnuswamy MN

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Analysis of hydrophobic and charged patches and influence of medium- and long-range interactions in molecular chaperones.

机译：分析疏水和带电斑块以及分子伴侣中的中长期相互作用的影响。

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摘要

The amino acid composition of the aromatic residues Phe, Tyr and Trp are much less significant in chaperones and the residues Cys, Glu, His, Met and Pro vary significantly in chaperones compared to normal globular proteins. In the present work, we have analysed the hydrophobic and charged patches in molecular chaperones which provide more insight for a better understanding of chaperone folding. Also, we have investigated the role of medium- and long-range contacts in chaperones and the preference of amino acid residues influenced by these interactions. Furthermore, the role of hydrophobic and helix-forming residues and disulfide bonding in these interactions have been discussed.

机译：与伴侣球蛋白相比，伴侣蛋白中芳香族残基Phe，Tyr和Trp的氨基酸组成不那么重要，而伴侣蛋白中的Cys，Glu，His，Met和Pro残基则有很大差异。在目前的工作中，我们已经分析了分子伴侣中的疏水和带电补丁，为更好地了解伴侣折叠提供了更多的见识。此外，我们研究了分子伴侣中和远程接触的作用以及受这些相互作用影响的氨基酸残基的偏好。此外，已经讨论了疏水和螺旋形成残基以及二硫键在这些相互作用中的作用。

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《Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena》 |1998年第2期|共9页
作者
Kumarevel TS; Gromiha MM; Ponnuswamy MN;
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正文语种 eng
中图分类生物化学;生物物理学;
关键词
Molecular Chaperones; Amino Acids; 分子监控蛋白类;

机译：Molecular Chaperones;Amino Acids;分子监控蛋白类;

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1. Analysis of hydrophobic and charged patches and influence of medium- and long-range interactions in molecular chaperones. [J] . Kumarevel TS, Gromiha MM, Ponnuswamy MN Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena . 1998,第2期

机译：分析疏水和带电斑块以及分子伴侣中的中长期相互作用的影响。
2. Influence of Molecular Dipole Orientations on Long-Range Exponential Interaction Forces at Hydrophobic Contacts in Aqueous Solutions [J] . Kai Kristiansen, Philipp Stock, Theodoros Baimpos, ACS nano . 2014,第10期

机译：分子偶极子取向对水溶液中疏水接触的长距离指数相互作用力的影响
3. Influence of a co-substituted A-site on structural characteristics and ferroelectricity of (Pb, Ba, Ca)TiO3 complex perovskites: analysis of local-, medium- and long-range order [J] . D. S. L. Pontes, F. M. Pontes, L. F. da Silva Journal of Sol-Gel Science and Technology . 2014,第3期

机译：共取代的A-位对（Pb，Ba，Ca）TiO3复合钙钛矿结构特征和铁电的影响：局部，中和远距离有序分析
4. Spectroscopic and calorimetric investigations on the influence of calcium ions on the polyamine negatively charged phospholipid molecular interactions [C] . Alessandro Bertoluzza, S.Bonora Univ. di Bologna Bologna Italy, G.Fini Univ. di Bologna Bologna Italy, International conference on laser applications in life sciences . 1993

机译：对钙离子对多胺对多胺带负电荷磷脂分子相互作用影响的光谱和量热研究
5. Molecular Dynamics Simulations Study of Hydrophilic and Hydrophobic Interactions between Nanoscale Particles [D] . Eun, Changsun 2010

机译：纳米级粒子之间的亲水和疏水相互作用的分子动力学模拟研究
6. Introduction of short-range restrictions in a protein-folding algorithm involving a long-range geometrical restriction and short- medium- and long-range interactions [O] . H. Meirovitch, H. A. Scheraga 1981

机译：在蛋白质折叠算法中引入短距离限制涉及到长距离几何限制以及短距离中距离和长距离相互作用
7. Influence of molecular dipole orientations on long-range exponential interaction forces at hydrophobic contacts in aqueous solutions [O] . Kristiansen, K., Stock, P., Baimpos, T., 2014

机译：分子偶极取向对水溶液中疏水接触的长程指数相互作用力的影响

Analysis of hydrophobic and charged patches and influence of medium- and long-range interactions in molecular chaperones.

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