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首页> 外文期刊>Drug information journal >Clinical Data for Informed Medication Use in Pregnancy: Strengths, Limitations, Gaps, and a Need to Continue Moving Forward
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Clinical Data for Informed Medication Use in Pregnancy: Strengths, Limitations, Gaps, and a Need to Continue Moving Forward

机译：妊娠知情用药的临床数据：优势，局限，差距以及需要继续前进

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The objective of this paper is to explore the strengths, weaknesses, gaps, and needs in research on medication use in pregnancy, where opportunities have been bypassed to develop standards and collaborations for collecting data to better understand how medications can impact clinical outcomes in pregnant women and developing fetuses. The availability of existing data and the methods of its capture are reviewed, including registries, claims and health record databases, and meta-analyses. The paper focuses on why these efforts have not fundamentally provided benefit-risk information and clinical treatment algorithms for medication use in pregnant women. Methodological issues, such as lack of standardization and central data collection, are discussed. Common barriers are examined, including a lack of awareness and education, cultural hurdles, collaboration deficiency, and an insufficient development of new data collection methods.
机译：本文的目的是探讨妊娠药物使用研究的优势，劣势，差距和需求，在这里绕过了机会来制定标准和合作以收集数据，以更好地了解药物如何影响孕妇的临床结果和发育中的胎儿。审查了现有数据的可用性及其捕获方法，包括注册表，索赔和健康记录数据库以及荟萃分析。本文着眼于为什么这些努力没有从根本上为孕妇用药提供受益风险信息和临床治疗算法。讨论了方法论问题，例如缺乏标准化和中央数据收集。研究了常见的障碍，包括缺乏意识和教育，文化障碍，协作不足以及新数据收集方法开发不足。

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