...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Drug news & perspectives >5-HT(2C) receptor agonists as an innovative approach for psychiatric disorders.
【24h】

5-HT(2C) receptor agonists as an innovative approach for psychiatric disorders.

机译：5-HT（2C）受体激动剂作为精神疾病的一种创新方法。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Modulating activity at the 5-HT(2C) receptor holds a tremendous amount of therapeutic promise in multiple psychiatric indications. However, the signaling and regulation of the 5-HT(2C) receptor is highly complex due to multiple signaling pathways and agonist-directed trafficking of this receptor. Moreover, the 5-HT(2C) receptor is differentially regulated via RNA editing in multiple psychiatric disorders and following either pharmacological or environmental manipulation. Direct and indirect data suggest that both agonists and antagonists may provide benefits in several disorders. The current review highlights the underlying complexities of this area and provides the rationale for using 5-HT(2C) agonists in the treatment of both schizophrenia and depressive disorders. (c) 2007 Prous Science. All rights reserved.
机译：在5-HT（2C）受体的调节活性在多种精神病适应症中拥有巨大的治疗前景。但是，由于多种信号通路和激动剂指导该受体的运输，5-HT（2C）受体的信号传导和调节高度复杂。此外，5-HT（2C）受体在多种精神疾病中以及在药理或环境操作后，通过RNA编辑受到差异调节。直接和间接数据表明，激动剂和拮抗剂均可在多种疾病中提供益处。当前的评论突出了这一领域的潜在复杂性，并提供了使用5-HT（2C）激动剂治疗精神分裂症和抑郁症的基本原理。 （c）2007 Prous科学。版权所有。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号