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首页> 外文期刊>Journal of Biomechanics >Flow oscillation-A measure to predict the surgery outcome for obstructed sleep apnea (OSA) subject
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Flow oscillation-A measure to predict the surgery outcome for obstructed sleep apnea (OSA) subject

机译：流量振荡-一种预测阻塞性睡眠呼吸暂停（OSA）受试者手术结局的措施

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摘要

Obstructed sleep apnea (OSA) is a common disorder which may need surgery to widen the airway; however the success rate of surgery is limited. Here we report a finding that could be used to predict the outcome of the OSA surgery. We found that inspiratory flow oscillates due to flow separation near the larynx, and the resulting periodic signal (3-5. Hz) is an intrinsic property of breathing. This flow oscillating signal may be the afferent stimulus to trigger respiratory events. It is found that the flow oscillation is attenuated for the OSA subjects. The computational fluid dynamics (CFD) simulation reveals that there exists flow separation near larynx and this separation is severely weakened in the OSA upper airway model. It is believed that the flow oscillating signal can serve as the measure to quantify the breathing quality of an OSA subject. This makes it possible to predict the surgery outcome of the OSA subject by applying CFD simulation.
机译：阻塞性睡眠呼吸暂停（OSA）是一种常见疾病，可能需要进行手术以扩大气道。但是手术的成功率是有限的。在这里，我们报告一项发现，可用于预测OSA手术的结果。我们发现，由于喉部附近的血流分离，吸气流量发生振荡，并且所产生的周期性信号（3-5。Hz）是呼吸的固有特性。该流动振荡信号可能是触发呼吸事件的传入刺激。发现对于OSA对象，流动振荡被衰减。计算流体动力学（CFD）仿真显示，在喉部附近存在流动分离，并且在OSA上呼吸道模型中该分离被严重削弱。据信，流动振荡信号可以用作量化OSA对象的呼吸质量的量度。这使得通过应用CFD模拟来预测OSA受试者的手术结局成为可能。

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