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首页> 外文期刊>Journal of Biomechanics >Realistic virtual intracranial stenting and computational fluid dynamics for treatment analysis
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Realistic virtual intracranial stenting and computational fluid dynamics for treatment analysis

机译：逼真的虚拟颅内支架置入术和用于治疗分析的计算流体动力学

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摘要

In order to support the decisions of medical experts and to develop better stent designs, the availability of a simulation tool for virtual stenting would be extremely useful. An innovative virtual stenting technique is described in this work, which is directly applicable for complex patient-specific geometries. A basilar tip aneurysm provided for the Virtual Intracranial Stenting Challenge 2010 is considered to demonstrate the advantages of this approach. A free-form deformation is introduced for a wall-tight stent deployment. Numerical flow simulations on sufficiently fine computational meshes are performed for different configurations in order to characterize the inflow rate into the aneurysm and the corresponding residence time in the aneurysm sac. A Neuroform and a SILK stent have been deployed at various locations and the computed residence times have been evaluated and compared, demonstrating the advantage associated with a lower stent porosity. It has been found that the SILK stent leads to a large increase in the residence time and to a significant reduction in the maximum wall shear stress in the aneurysm sac. This is only observed when placing the stent in the appropriate position, showing that virtual stenting might be employed for operation support.
机译：为了支持医学专家的决定并开发更好的支架设计，用于虚拟支架的仿真工具的可用性将非常有用。在这项工作中描述了一种创新的虚拟支架技术，该技术直接适用于特定于患者的复杂几何形状。为2010年虚拟颅内支架挑战术提供的基底提示动脉瘤被认为是证明这种方法的优势。引入了自由形式的变形以用于壁密性支架展开。针对不同的配置对足够精细的计算网格进行数值模拟，以表征流入动脉瘤的流量以及在动脉瘤囊中的相应停留时间。 Neuroform和SILK支架已部署在各个位置，并且已评估并比较了计算的停留时间，证明了较低的支架孔隙率具有优势。已经发现，SILK支架导致滞留时间大大增加，并且大大减小了动脉瘤囊中的最大壁剪切应力。仅当将支架放置在适当位置时才能观察到这一点，这表明可以将虚拟支架用于操作支持。

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