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Wave intensity analysis in air-filled flexible vessels

机译:充气式柔性容器中的波强度分析

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Wave intensity analysis (WIA) is an analytical technique generally used to investigate the propagation of waves in the cardiovascular system. Despite its increasing usage in the cardiovascular system, to our knowledge WIA has never been applied to the respiratory system. Given the analogies between arteries and airways (i.e. fluid flow in flexible vessels), the aim of this work is to test the applicability of WIA with gas flow instead of liquid flow. The models employed in this study are similar to earlier studies used for arterial investigations. Simultaneous pressure (P) and velocity (U) measurements were initially made in a single tube and then in several flexible tubes connected in series. Wave speed was calculated using the foot-to-foot method (c(f)), which was used to separate analytically the measured P and U waveforms into their forward and backward components. Further, the data were used to calculate wave intensity, which was also separated into its forward and backward components. Although the measured wave speed was relatively high, the results showed that the onsets and the nature of reflections (compression/expansion) derived with WIA, corresponded well to those anticipated using the theory of waves in liquid-filled elastic tubes. On average the difference between the experimental and theoretical arrival time of reflection was 6.1% and 3.6% for the single vessel and multivessel experiment, respectively. The results suggest that WIA can provide relatively accurate information on reflections in air-filled flexible tubes, warranting further studies to explore the full potential of this technique in the respiratory system. (C) 2015 Published by Elsevier Ltd.
机译:波浪强度分析(WIA)是一种通常用于研究波浪在心血管系统中传播的分析技术。尽管WIA在心血管系统中的使用越来越多,但据我们所知,WIA从未应用于呼吸系统。考虑到动脉和气道之间的类比(即柔性血管中的流体流动),这项工作的目的是测试WIA在气体流动而不是液体流动中的适用性。本研究中使用的模型与用于动脉研究的早期研究相似。首先在单个管中然后同时在串联的多个挠性管中同时进行压力(P)和速度(U)测量。使用脚对脚方法(c(f))计算波速,该方法用于将测得的P和U波形解析地分离为正向和反向分量。此外,该数据用于计算波强度,波强度也分为其前向和后向分量。尽管测得的波速较高,但结果表明,由WIA产生的反射的开始和性质(压缩/扩展)与使用液体填充的弹性管中的波理论所预期的非常吻合。对于单容器和多容器实验,反射的实验到达时间和理论到达时间之间的平均差异分别为6.1%和3.6%。结果表明,WIA可以提供有关充气软管中反射的相对准确的信息,值得进一步研究以探索该技术在呼吸系统中的全部潜力。 (C)2015由Elsevier Ltd.出版

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