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首页> 外文期刊>Journal of Biomechanics >The biomechanical properties of canine skin measured in situ by uniaxial extension
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The biomechanical properties of canine skin measured in situ by uniaxial extension

机译：单轴拉伸原位测量犬皮肤的生物力学性能

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Introduction: A uniaxial extension system was setup to analyze the mechanical properties of dog skin. Material and methods: Pads were glued onto dog skin with constant reproducible geometrical parameters and the extension force was measured as a function of the extension values. Forty-one sites (82 cycling tests) were investigated in situ on 11 canine cadavers, half of them after surgically isolating the test area from the surrounding skin. Series of loading-unloading cycles of up to 5 N or 10 N or both loads were performed on each site. The elastic properties and the dissipative effects were characterized respectively by evaluating the secant Rigidity at maximum loads and the Fraction of dissipated energy. Results: A hysteresis phenomenon, implying the need for preconditioning to attain equilibrium cycles, was apparent during mechanical characterization. Polynomial expressions were used to relate the measured Rigidities and the Fractions of dissipated energy with or without sample isolation. The latter were less affected by isolation. The ratios between the Rigidities at 5 N to those at 10 N displayed non-linearity in the investigated extension range in contrary to the Fractions of dissipated energy. Discussion/conclusion: The parameters confirming the dissipative non-linear elastic behavior of dog skin were identified and the correlation between Rigidity and Fraction of dissipated energy on isolated and non-isolated skin samples was quantitatively determined. This extension setup can now be used as a "true in vivo" mapping tool to determine the mechanical characteristics of the skin during healing processes or during the study of Human skin disease with the dog as an animal model.
机译：简介：建立了单轴拉伸系统来分析狗皮的机械性能。材料和方法：用恒定的可重复几何参数将护垫粘贴到狗皮上，并根据延伸值测量延伸力。在11只犬尸体上进行了41个部位（82次循环试验）的现场调查，其中一半是通过手术将试验区域与周围皮肤隔离开的。在每个站点上执行了一系列最多5 N或10 N的加载/卸载循环或两次加载。通过评估最大载荷下的割线刚度和耗散能量的分数来分别表征其弹性性能和耗散效果。结果：在机械表征过程中，明显出现了磁滞现象，这意味着需要进行预处理才能达到平衡循环。多项式表达式用于关联测量的刚度和有或没有样品隔离的耗散能量的分数。后者受隔离的影响较小。 5 N刚度与10 N刚度之间的比率在研究的扩展范围内显示非线性，这与耗散能量的分数相反。讨论/结论：确定了确认狗皮肤耗散非线性弹性行为的参数，并定量确定了隔离和非隔离皮肤样品上耗散能量的刚度与耗散率之间的相关性。现在可以将此扩展设置用作“真实的体内”映射工具，以在将狗作为动物模型的愈合过程中或研究人类皮肤病期间确定皮肤的机械特性。

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