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首页> 外文期刊>Journal of Biomechanics >Effect of growth plate geometry and growth direction on prediction of proximal femoral morphology
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Effect of growth plate geometry and growth direction on prediction of proximal femoral morphology

机译：生长板的几何形状和生长方向对股骨近端形态预测的影响

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Mechanical stimuli play a significant role in the process of endochondral growth. Thus far, approaches to understand the endochondral mechanical growth rate have been limited to the use of approximated location and geometry of the growth plate. Furthermore, growth has been simulated based on the average deflection of the growth plate or of the femoral neck. It has also been reported in the literature that the growth plate lies parallel to one of the principal stresses acting on it, to reduce the shear between epiphysis and diaphysis. Hence the current study objectives were (1) to evaluate the significance of a subject-specific finite element model of the femur and growth plate compared to a simplified growth plate model and (2) to explore the different growth direction models to better understand proximal femoral growth mechanisms. A subject-specific finite element model of an able-bodied 7-year old child was developed. The muscle forces and hip contact force were computed for one gait cycle and applied to a finite element model to determine the specific growth rate. Proximal femoral growth was simulated for two different growth direction models: femoral neck deflection direction and principal stress direction. The principal stress direction model captured the expected tendency for decreasing the neck shaft angle and femoral anteversion for both growth plate models. The results of this study suggest that the subject-specific geometry and consideration of the principal stress direction as growth direction may be a more realistic approach for correct prediction of proximal femoral growth morphology. (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
机译：机械刺激在软骨内生长过程中起重要作用。到目前为止，了解软骨内机械生长速率的方法仅限于使用生长板的近似位置和几何形状。此外，已经基于生长板或股骨颈的平均偏转来模拟生长。在文献中还报道了生长板平行于作用在其上的主要应力之一，以减小骨epi和骨干之间的剪切。因此，当前的研究目标是（1）与简化的生长板模型相比，评估特定对象的股骨和生长板有限元模型的重要性;（2）探索不同的生长方向模型以更好地了解股骨近端增长机制。建立了一个健全的7岁儿童的特定于学科的有限元模型。计算一个步态周期的肌肉力和髋部接触力，并将其应用于有限元模型，以确定比生长速率。针对两种不同的生长方向模型模拟了股骨近端生长：股骨颈偏转方向和主应力方向。主应力方向模型捕获了两种生长板模型的减小颈轴角度和股骨前倾的预期趋势。这项研究的结果表明，特定对象的几何形状以及将主应力方向视为生长方向可能是更正确地预测股骨近端生长形态的方法。 （C）2016作者。由Elsevier Ltd.发布。这是CC BY-NC-ND许可（http://creativecommons.org/licenses/by-nc-nd/4.0/）下的开放获取文章。

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