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首页> 外文期刊>Journal of Biomechanics >Flow-tissue interaction with compliance mismatch in a model stented artery
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Flow-tissue interaction with compliance mismatch in a model stented artery

机译：模型支架动脉中的顺应性失配引起的流组织相互作用

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The insertion of an endovascular prosthesis is known to have a thrombogenic effect that is also a consequence of the interaction between the flowing blood and the stented arterial segment; in fact the prosthesis induces a compliance mismatch and a possible small expansion along the vessel that eventually gives rise to an anomalous distribution of wall shear stresses. The fluid dynamics inside a rectilinear elastic vessel with compliance and section variation is studied here numerically. A recently introduced perturbative approach is employed to model the interaction between the fluid and the elastic tissue; this approximate technique is first validated by comparison with a complete solution within a simple one-dimensional model of the same system. Then it is applied to an axisymmetric model in order to evaluate the flow dynamics and the distribution of wall shear stress in the stented vessel. Compliance mismatch is shown to produce more intense negative wall shear stresses in the stented segment while rapid variations of wall shear stress are found at the stent ends. These effects are enhanced when the prosthesis is accompanied by a small increase of the vessel lumen. (C) 2003 Elsevier Ltd. All rights reserved. [References: 24]
机译：众所周知，血管内假体的插入具有血栓形成作用，这也是流动的血液与带支架的动脉段之间相互作用的结果。实际上，假体会引起顺应性不匹配，并可能导致沿血管的微小扩张，最终导致壁切应力的反常分布。在此，对具有顺应性和截面变化的直线弹性容器内部的流体动力学进行了数值研究。最近采用了一种摄动方法来模拟流体与弹性组织之间的相互作用。首先，通过与同一系统的简单一维模型中的完整解决方案进行比较，验证这种近似技术。然后将其应用于轴对称模型，以评估带支架血管中的流动动力学和壁切应力的分布。顺应性失配显示出在支架段中产生更大的负壁剪切应力，而在支架末端发现壁切应力快速变化。当假体伴随着血管腔的少量增加时，这些效果会增强。 （C）2003 Elsevier Ltd.保留所有权利。 [参考：24]

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