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首页> 外文期刊>Journal of Biomechanics >Analysis of the transient expansion behavior and design optimization of coronary stents by finite element method.
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Analysis of the transient expansion behavior and design optimization of coronary stents by finite element method.

机译：冠状动脉支架的瞬态扩展行为分析及有限元优化设计。

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摘要

The percutaneous transluminal coronary angioplasty (PTCA) assisted with stenting technique has become a primary therapy to coronary heart disease. In practice, the structure conditions of both ends of stent/balloon system influence a stent's instantaneous expansion behavior. The transitory nonuniform expansion, the so-called dogboning, of stent/balloon system is one of the main reasons to induce the acute vascular injury at the two edges of a stent. This kind of vascular injury has a close relationship with the in-stent restenosis. In the present paper, the finite element method (FEM) was applied to simulate the transient expansion process of stent/balloon system with different stent structure and balloon length under the internal pressure. And two types of stent and six collocations of stent and balloon were modeled. Modeling results showed that the dogboning phenomenon can be eliminated by improving geometry of a stent or/and varying the length of balloon over stent. The above modeled results were further confirmed by following in situ observation.
机译：借助支架技术的经皮腔内冠状动脉成形术（PTCA）已成为冠心病的主要治疗方法。在实践中，支架/气囊系统两端的结构条件会影响支架的瞬时膨胀行为。支架/气囊系统的瞬时不均匀膨胀，即所谓的“粘骨”，是在支架的两个边缘引起急性血管损伤的主要原因之一。这种血管损伤与支架内再狭窄密切相关。本文采用有限元方法（FEM）模拟了在内部压力下具有不同支架结构和气囊长度的支架/气囊系统的瞬态膨胀过程。并建模了两种类型的支架以及支架和球囊的六个搭配。建模结果表明，可以通过改善支架的几何形状或/和更改支架上球囊的长度来消除狗骨头现象。通过以下原位观察进一步证实了上述建模结果。

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