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Redistribution of strain and curvature in the porcine anterior lens capsule following a continuous circular capsulorhexis

机译:连续圆形撕囊后猪前晶状体囊的应变和曲率的重新分布

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摘要

Cataract surgery is the most commonly performed surgical procedure in the US, it consists of three steps: introduction of a hole into the lens capsule, removal of the clouded lens through this access hole, and insertion of an artificial lens. We hypothesize that errant behavior by the residual epithelial cells of the lens capsule following surgery are due, in part, to surgically-induced changes of the native stress and strain fields in the lens capsule. Because the capsular bag can be regarded mechanically as a membrane, here we study changes in curvature and strains due to the most common means of introducing the initial access hole: a continuous circular capsulorhexis (CCC). We show that a modest sized CCC increases circumferential strains and decreases meridional strains by up to similar to 20% and that curvatures change by up to similar to 13%, particularly near the edge of the CCC. We submit that such changes can induce mechanobiological responses that are responsible, in part, for some of the long-term complications following cataract surgery. (c) 2005 Elsevier Ltd. All rights reserved.
机译:白内障手术是美国最常用的外科手术,它包括三个步骤:在晶状体囊中引入一个孔,通过该进入孔取出浑浊的晶状体,以及插入人工晶状体。我们假设手术后晶状体囊的残留上皮细胞的错误行为部分归因于手术引起的晶状体囊中固有应力和应变场的变化。由于囊袋可以机械地视为膜,因此在这里我们研究由于引入初始进入孔的最常用方法:连续圆形撕囊术(CCC)而引起的曲率和应变的变化。我们显示出适度大小的CCC会增加周向应变,并将子午线应变降低多达20%左右,并且曲率的变化幅度最高可达13%,尤其是在CCC边缘附近。我们认为,这种改变可引起机械生物学反应,部分原因是白内障手术后的一些长期并发症。 (c)2005 Elsevier Ltd.保留所有权利。

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