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Tensile cervical facet capsule ligament mechanics: Failure and subfailure responses in the rat

机译:拉伸颈小平面囊韧带力学:大鼠的衰竭和亚衰竭反应

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Clinical, epidemiological, and biomechanical studies suggest the involvement of the cervical facet joint in neck pain. Mechanical studies have suggested the facet capsular ligament to be at risk for subfailure tensile injury during whiplash kinematics of the neck. Ligament mechanical properties can be altered by subfailure injury and such loading can induce cellular damage. However, at present, there is no clear understanding of the physiologic context of subfailure facet capsular ligament injury and mechanical implications for whiplash-related pain. Therefore, this study aimed to define a relationship between mechanical properties at failure and a subfailure condition associated with pain for tension in the rat cervical facet capsular ligament. Tensile failure studies of the C6/C7 rat cervical facet capsular ligament were performed using a customized vertebral distraction device. Force and displacement at failure were measured and stiffness and energy to failure were calculated. Vertebral motions and ligament deformations were tracked and maximum principal strains and their directions were calculated. Mean tensile force at failure (2.96 +/- 0.69 N) was significantly greater (p < 0.005) than force at subfailure (1.17 +/- 0.48 N). Mean ligament stiffness to failure was 0.75 +/- 0.27 N/mm. Maximum principal strain at failure (41.3 +/- 20.0%) was significantly higher (p = 0.003) than the corresponding subfailure value (23.1 +/- 9.3%). This study determined that failure and a subfailure painful condition were significantly different in ligament mechanics and findings provide preliminary insight into the relationship between mechanics and pain physiology for this ligament. Together with existing studies, these findings offer additional considerations for defining mechanical thresholds for painful injuries. (c) 2005 Elsevier Ltd. All rights reserved.
机译:临床,流行病学和生物力学研究表明,颈部小关节受累于颈部疼痛。力学研究表明,在颈的颈椎运动中,小关节囊韧带存在亚失败性拉伸损伤的风险。韧带的机械性能会因亚损伤而改变,这种载荷会引起细胞损伤。然而,目前,对于亚失败小平面囊韧带损伤的生理环境以及与鞭打相关的疼痛的机械影响尚无明确的了解。因此,本研究旨在确定大鼠颈椎小面囊韧带断裂时的力学性能与与疼痛相关的亚衰竭状态之间的关系。使用定制的椎骨牵引装置对C6 / C7大鼠颈小面囊韧带进行了拉伸破坏研究。测量了破坏时的力和位移,并计算了破坏时的刚度和能量。跟踪椎骨运动和韧带变形,并计算最大主应变及其方向。失效时的平均拉伸力(2.96 +/- 0.69 N)明显大于未失效时的平均拉伸力(p <0.005)(1.17 +/- 0.48 N)。韧带断裂的平均刚度为0.75 +/- 0.27 N / mm。失效时的最大主应变(41.3 +/- 20.0%)明显高于相应的亚失效值(23.1 +/- 9.3%)(p = 0.003)。这项研究确定韧带力学上的衰竭和亚衰竭疼痛状况显着不同,研究结果为该韧带的力学与疼痛生理之间的关系提供了初步的见识。与现有研究一起,这些发现为定义疼痛性损伤的机械阈值提供了更多考虑因素。 (c)2005 Elsevier Ltd.保留所有权利。

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