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首页> 外文期刊>Journal of Biomechanics >An approach to the simulation of fluid-structure interaction in the aortic valve.
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An approach to the simulation of fluid-structure interaction in the aortic valve.

机译：一种模拟主动脉瓣中流固耦合的方法。

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摘要

A pair of finite element models has been employed to study the interaction of blood flow with the operation of the aortic valve. A three-dimensional model of the left ventricle with applied wall displacements has been used to generate data for the spatially and time-varying blood velocity profile across the aortic aperture. These data have been used as the inlet loading conditions in a three-dimensional model of the aortic valve and its surrounding structures. Both models involve fluid-structure interaction and simulate the cardiac cycle as a dynamic event. Confidence in the models was obtained by comparison with data obtained in a pulse duplicator. The results show a circulatory flow being generated in the ventricle which produces a substantially axial flow through the aortic aperture. The aortic valve behaves in an essentially symmetric way under the action of this flow, so that the pressure difference across the leaflets is approximately uniform. This work supports the use of spatially uniform but temporally variable pressure distributions across the leaflets in dry or structural models of aortic valves. The study is a major advance through its use of truly three-dimensional geometry, spatially non-uniform loading conditions for the valve leaflets and the successful modelling of progressive contact of the leaflets in a fluid environment.
机译：已使用一对有限元模型来研究血流与主动脉瓣膜的相互作用。左心室的三维模型及其施加的壁位移已被用于生成跨主动脉孔的时空血流速度分布数据。这些数据已被用作主动脉瓣及其周围结构的三维模型中的入口载荷条件。两种模型都涉及流体-结构相互作用，并且将心动周期模拟为动态事件。通过与在脉冲复制器中获得的数据进行比较，获得了模型的置信度。结果显示在心室中产生循环血流，该循环血流产生通过主动脉孔的基本上轴向的血流。在这种流动的作用下，主动脉瓣以基本上对称的方式起作用，从而跨小叶的压差大致均匀。这项工作支持在主动脉瓣的干燥或结构模型中跨小叶使用空间均匀但随时间变化的压力分布。这项研究是一项重大进展，因为它使用了真正的三维几何形状，瓣膜小叶的空间不均匀加载条件，并且成功地模拟了流体环境中小叶的渐进接触。

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