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首页> 外文期刊>Journal of Biomechanics >ELONGATION MECHANISM OF COLLAGEN FIBRILS AND FORCE-STRAIN RELATIONS OF TENDON AT EACH LEVEL OF STRUCTURAL HIERARCHY
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ELONGATION MECHANISM OF COLLAGEN FIBRILS AND FORCE-STRAIN RELATIONS OF TENDON AT EACH LEVEL OF STRUCTURAL HIERARCHY

机译:每个结构层次上胶原蛋白纤维的伸长机理和肌腱的力-应变关系

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摘要

Tension-induced structural changes in bovine Achilles tendon collagen al each level of the hierarchy structure were investigated by means of the X-ray diffraction method. In order to estimate the straining mechanism in a collagen fibril, three elementary models for molecular elongation and rearrangement of collagen fibril were proposed on the basis of the Hodge-Petruska model: [1] molecular elongation, [2] increase in gap region and [3] relative slippage of laterally adjoining molecules. The characteristic 67 nm D-period of a collagen fibril increases with applied force. A Hookean-type force-strain curve was obtained for the D-period while the force-strain relation for the tendon was non-Hookean. The relative intensity of third-order reflection of the D-period to that of the second-order one, I-3/I-2, decreased with the applied force. This decrease in I-3/I-2 indicates a decrease in the ratio of the overlap region of collagen fibril to the D-period, O/D, which was analyzed on the basis of the Hodge-Petruska model. Decomposition of the observed strain in the D-period, epsilon(D), into these three deforming modes revealed that the major contribution to epsilon(D) originated from mode [1], molecular elongation. It was deduced that a fibril is mechanically composed of molecules connected serially to each other. Copyright (C) 1996 Elsevier Science Ltd. [References: 22]
机译:通过X射线衍射法研究了牛跟腱胶原蛋白中张力诱导的结构变化,以及各个层次结构的水平。为了估计胶原蛋白原纤维的应变机制,在Hodge-Petruska模型的基础上,提出了三种胶原蛋白原纤维分子伸长和重排的基本模型:[1]分子伸长,[2]间隙区增加和[ 3]横向邻接分子的相对滑动。胶原纤维的特征性67 nm D周期随施加的力而增加。对于D周期,获得了Hookean型的力-应变曲线,而与腱的力-应变关系却不是霍克式的。 D周期相对于二阶I-3 / I-2的三次反射的相对强度随施加的力而降低。 I-3 / I-2的减少表明胶原原纤维重叠区域与D时段O / D的比率降低,这是根据Hodge-Petruska模型进行分析的。在D周期中观察到的应变epsilon(D)分解为这三种变形模式显示,对epsilon(D)的主要贡献来自模式[1],即分子伸长。可以推断,原纤维是由相互串联的分子机械地构成的。版权所有(C)1996 Elsevier Science Ltd. [引用:22]

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