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首页> 外文期刊>Journal of Biomechanics >How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint.
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How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint.

机译：半月板附件的刚度和半月板材料特性如何影响使用经过验证的人膝关节有限元模型计算出的胫股接触压力。

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In an effort to prevent degeneration of articular cartilage associated with meniscectomies, both meniscal allografts and synthetic replacements are subjects of current interest and investigation. The objectives of the current study were to (1) determine whether a transversely isotropic, linearly elastic, homogeneous material model of the meniscal tissue is necessary to achieve a normal contact pressure distribution on the tibial plateau, (2) determine which material and boundary condition (attachments) parameters affect the contact pressure distribution most strongly, and (3) set tolerances on these parameters to restore the contact pressure distribution to within a specified error. To satisfy these objectives, a finite element model of the tibio-femoral joint of a human cadaveric knee (including both menisci) was used to study the contact pressure distribution on the tibial plateau. To validate the model, the contact pressure distribution on the tibial plateau was measured experimentally in the same knee used to create the model. Within physiologically reasonable bounds on five material parameters and four attachment parameters associated with a meniscal replacement, an optimization was performed under 1200 N of compressive load on the set of nine parameters to minimize the difference between the experimental and model results. The error between the experimental and model contact variables was minimized to 5.4%. The contact pressure distribution of the tibial plateau was sensitive to the circumferential modulus, axial/radial modulus, and horn stiffness, but relatively insensitive to the remaining six parameters. Consequently, both the circumferential and axial/radial moduli are important determinants of the contact pressure distribution, and hence should be matched in the design and/or selection of meniscal replacements. In addition, during surgical implantation of a meniscal replacement, the horns should be attached with high stiffness bone plugs, and the attachments of the transverse ligament and deep medial collateral ligament should be restored to minimize changes in the contact pressure distribution, and thereby possibly prevent the degradation of articular cartilage.
机译：为了防止与半月板切除术相关的关节软骨退变，半月形同种异体移植物和人工合成的替代物都是当前关注和研究的课题。当前研究的目的是（1）确定是否需要横向半同性，线性弹性，均质的半月板组织材料模型来实现胫骨平台上的正常接触压力分布;（2）确定哪种材料和边界条件（附件）参数对接触压力分布的影响最大，并且（3）在这些参数上设置公差以将接触压力分布恢复到指定误差内。为了满足这些目标，使用人尸体膝盖（包括两个半月板）的胫股关节的有限元模型来研究胫骨平台上的接触压力分布。为了验证模型，在创建模型所用的同一膝盖上通过实验测量了胫骨平台上的接触压力分布。在与半月板置换相关的五个材料参数和四个附着参数的生理合理范围内，在1200 N压缩载荷下对九个参数进行了优化，以最大程度地减少实验结果与模型结果之间的差异。实验和模型接触变量之间的误差最小化为5.4％。胫骨平台的接触压力分布对周向模量，轴向/径向模量和变幅杆刚度敏感，但对其余六个参数相对不敏感。因此，圆周和轴向/径向模量都是接触压力分布的重要决定因素，因此在设计和/或选择半月板替代物时应匹配。此外，在半月板置换术的外科手术植入过程中，应使用高刚度的骨栓连接牛角，并应恢复横韧带和深内侧副韧带的附着，以最大程度地减少接触压力分布的变化，从而可能防止关节软骨的退化。

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