...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Biomechanics >A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysms.
【24h】

A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysms.

机译：一种用于估计腹主动脉瘤壁应力的解耦流体结构方法。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abdominal aortic aneurysm (AAA) is a localized dilatation of the aortic wall. The lack of an accurate AAA rupture risk index remains an important problem in the clinical management of the disease. To accurately estimate AAA rupture risk, detailed information on patient-specific wall stress distribution and aortic wall tissue yield stress is required. A complete fluid structure interaction (FSI) study is currently impractical and thus of limited clinical value. On the other hand, isolated static structural stress analysis based on a uniform wall loading is a widely used approach for AAA rupture risk estimation that, however, neglects the flow-induced wall stress variation. The aim of this study was to assess the merit of a decoupled fluid structure analysis of AAA wall stress. Anatomically correct, patient specific AAA wall models were created by 3D reconstruction of computed tomography images. Flow simulations were carried out with inflow and outflow boundary conditions obtained from patient extracted data. Static structural stress analysis was performed applying both a uniform pressure wall loading and a flow induced non-uniform pressure distribution obtained during early systolic deceleration. For the structural analysis, a hyperelastic arterial wall model and an elastic intraluminal thrombus model were assumed. The results of this study demonstrate that although the isolated static structural stress analysis approach captures the gross features of the stress distribution it underestimates the magnitude of the peak wall stress by as much as 12.5% compared to the proposed decoupled fluid structure approach. Furthermore, the decoupled approach provides potentially useful information on the nature of the aneurysmal sac flow.
机译：腹主动脉瘤（AAA）是主动脉壁的局部扩张。缺乏准确的AAA破裂风险指数仍然是该疾病临床管理中的重要问题。为了准确估计AAA破裂风险，需要有关患者特定壁应力分布和主动脉壁组织屈服应力的详细信息。目前尚无法进行完整的流体结构相互作用（FSI）研究，因此临床价值有限。另一方面，基于均匀壁载荷的孤立静态结构应力分析是用于AAA破裂风险评估的一种广泛使用的方法，但是却忽略了流动引起的壁应力变化。这项研究的目的是评估AAA壁应力的解耦流体结构分析的优点。通过计算机断层扫描图像的3D重建，创建解剖学上正确的，特定于患者的AAA壁模型。使用从患者提取的数据中获得的流入和流出边界条件进行流量模拟。进行静态结构应力分析，同时应用了均匀的压力壁载荷和在收缩期早期减速期间获得的由流动引起的非均匀压力分布。为了进行结构分析，假定了超弹性动脉壁模型和弹性腔内血栓模型。这项研究的结果表明，尽管孤立的静态结构应力分析方法捕获了应力分布的总体特征，但与拟议的解耦流体结构方法相比，它低估了峰值壁应力的幅度高达12.5％。此外，分离的方法提供了关于动脉瘤囊流动性质的潜在有用信息。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号