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首页> 外文期刊>Journal of Biomechanics >STABILITY OF MUSCLE FIBERS ON THE DESCENDING LIMB OF THE FORCE-LENGTH RELATION - A THEORETICAL CONSIDERATION
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STABILITY OF MUSCLE FIBERS ON THE DESCENDING LIMB OF THE FORCE-LENGTH RELATION - A THEORETICAL CONSIDERATION

机译:力长关系下降的肢体上肌肉纤维的稳定性-一个理论考虑

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摘要

For the past 40 years it has generally been accepted that the descending limb of the force-length (F-L) relation of muscle fibers is unstable; strong sarcomeres are thought to shorten onto the ascending limb of the F-L relation at the expense of weak sarcomeres which are stretched beyond the thin-thick myofilament overlap. This unstable behavior has not been demonstrated by direct observation but has been inferred indirectly, based on the negative slope of the F-L relation. Intuitively, the idea that the sarcomere length within skeletal muscle is unstable at any length within the normal working range would not be advantageous. Therefore, the purpose of this study was to identify analytically the mechanical conditions for which sarcomeres in a muscle fiber are stable. It was found that the mechanical conditions required for sarcomere and fiber stability could be associated with known properties of skeletal muscle fibers. Furthermore, it could be demonstrated that a fiber composed of a large number of sarcomeres can be stable, and still exhibit an apparently unstable (negatively sloped) descending limb of the F-L curve. [References: 26]
机译:在过去的40年中,人们普遍认为肌肉纤维的力长(F-L)关系的下降肢是不稳定的。认为强的肉瘤会缩短到F-L关系的上升肢体上,而以弱的肉瘤为代价,这些肉瘤会延伸超过薄的肌丝重叠部分。这种不稳定的行为尚未通过直接观察得到证实,但已根据F-L关系的负斜率间接推断出。直觉上,在正常工作范围内任何长度的骨骼肌中肌节长度都是不稳定的想法将是不利的。因此,本研究的目的是分析性地确定肌肉纤维中肉瘤稳定的机械条件。已经发现,肌节和纤维稳定性所需的机械条件可能与骨骼肌纤维的已知特性有关。此外,可以证明由大量肉瘤组成的纤维可以保持稳定,并且仍表现出F-L曲线的明显不稳定(负倾斜)的下降肢。 [参考:26]

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