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首页> 外文期刊>Journal of Biomechanics >Patient-specific initial wall stress in abdominal aortic aneurysms with a backward incremental method.
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Patient-specific initial wall stress in abdominal aortic aneurysms with a backward incremental method.

机译：用后向增量方法在腹主动脉瘤中患者特定的初始壁应力。

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摘要

Patient-specific wall stress simulations on abdominal aortic aneurysms may provide a better criterion for surgical intervention than the currently used maximum transverse diameter. In these simulations, it is common practice to compute the peak wall stress by applying the full systolic pressure directly on the aneurysm geometry as it appears in medical images. Since this approach does not account for the fact that the measured geometry is already experiencing a substantial load, it may lead to an incorrect systolic aneurysm shape. We have developed an approach to compute the wall stress on the true diastolic geometry at a given pressure with a backward incremental method. The method has been evaluated with a neo-Hookean material law for several simple test problems. The results show that the method can predict an unloaded configuration if the loaded geometry and the load applied are known. The effect of incorporating the initial diastolic stress has been assessed by using three patient-specific geometries acquired with cardiac triggered MR. The comparison shows that the commonly used approach leads to an unrealistically smooth systolic geometry and therefore provides an underestimation for the peak wall stress. Our backward incremental modelling approach overcomes these issues and provides a more plausible estimate for the systolic aneurysm volume and a significantly different estimate for the peak wall stress. When the approach is applied with a more complex material law which has been proposed specifically for abdominal aortic aneurysm similar effects are observed and the same conclusion can be drawn.
机译：与当前使用的最大横向直径相比，针对患者的特定于腹主动脉瘤的壁应力模拟可能为外科手术提供更好的标准。在这些模拟中，通常的做法是通过直接在医学图像中出现的动脉瘤几何形状上直接施加全收缩压来计算峰值壁应力。由于这种方法不能解决测量的几何体已经承受较大负荷的事实，因此可能会导致收缩期动脉瘤的形状不正确。我们已经开发出一种方法，可以使用后向增量方法在给定压力下计算真实舒张几何结构上的壁应力。该方法已通过新霍克材料定律进行了评估，以解决几个简单的测试问题。结果表明，如果已知加载的几何形状和所施加的载荷，则该方法可以预测未加载的配置。通过使用通过心脏触发的MR获得的三种特定于患者的几何形状，已经评估了合并初始舒张压的效果。比较结果表明，常用的方法导致收缩期几何形状不切实际，因此低估了峰值壁应力。我们的向后增量建模方法克服了这些问题，并为收缩期动脉瘤量提供了更合理的估计，并为峰值壁应力提供了明显不同的估计。当采用更复杂的材料法则（专门针对腹主动脉瘤提出）应用该方法时，会观察到类似的效果，并且可以得出相同的结论。

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