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首页> 外文期刊>Journal of Biomechanics >Meniscus replacement: Influence of geometrical mismatches on chondroprotective capabilities
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Meniscus replacement: Influence of geometrical mismatches on chondroprotective capabilities

机译：半月板置换：几何形状不匹配对软骨保护功能的影响

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The chondroprotective success of meniscal transplantation is variable. Poorly controlled factors such as a geometrical mismatch of the implant may be partly responsible. Clinical data, animal studies and cadaver experiments suggest that smaller transplants perform better than oversized, but clear evidence is lacking. The hypothesis of this study is that smaller menisci outperform larger ones because they distribute stresses more effectively at those particular locations that receive the highest loads. Consequently, collagen in the adjacent cartilage is protected from damage due to overstraining. Experimentally it is not possible to measure load distribution and collagen strain inside articular cartilage (AC). Therefore, a numerical model was used to determine the mechanical conditions throughout the depth of the AC. Meniscus implants with different sizes and mechanical properties were evaluated. These were compared with healthy and with meniscectomized joints. To account for the time-dependent behavior 600 s of loading was simulated; results were visualized after 1 s and 600 s.
机译：半月板移植的软骨保护成功率是可变的。诸如植入物的几何不匹配之类的不良控制因素可能是部分原因。临床数据，动物研究和尸体实验表明，较小的移植物比超大型移植物的性能更好，但缺乏明确的证据。这项研究的假设是，较小的弯液面优于较大的弯液面，因为它们在承受最高载荷的特定位置更有效地分散了应力。因此，保护​​了相邻软骨中的胶原免于因过度拉伸而受损。实验上不可能测量关节软骨（AC）内的负荷分布和胶原蛋白应变。因此，使用数值模型来确定整个AC深度的机械条件。对具有不同尺寸和机械性能的半月板植入物进行了评估。将这些与健康和半月板切除的关节进行比较。为了说明与时间有关的行为，模拟了600 s的加载; 1 s和600 s后可视化结果。

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