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首页> 外文期刊>Journal of biomedical informatics. >A fuzzy system for helping medical diagnosis of malformations of cortical development.
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A fuzzy system for helping medical diagnosis of malformations of cortical development.

机译：用于帮助医学诊断皮质发育畸形的模糊系统。

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Malformations of the cerebral cortex are recognized as a common cause of developmental delay, neurological deficits, mental retardation and epilepsy. Currently, the diagnosis of cerebral cortical malformations is based on a subjective interpretation of neuroimaging characteristics of the cerebral gray matter and underlying white matter. There is no automated system for aiding the observer in making the diagnosis of a cortical malformation. In this paper a fuzzy rule-based system is proposed as a solution for this problem. The system collects the available expert knowledge about cortical malformations and assists the medical observer in arriving at a correct diagnosis. Moreover, the system allows the study of the influence of the various factors that take part in the decision. The evaluation of the system has been carried out by comparing the automated diagnostic algorithm with known case examples of various malformations due to abnormal cortical organization. An exhaustive evaluation of the system by comparison with published cases and a ROC analysis is presented in the paper.
机译：大脑皮层畸形被认为是发育迟缓，神经系统缺陷，智力低下和癫痫的常见原因。当前，脑皮质畸形的诊断基于对脑灰质和潜在白质的神经影像学特征的主观解释。没有自动系统可以帮助观察者诊断皮层畸形。本文提出了一种基于模糊规则的系统作为该问题的解决方案。该系统收集有关皮质畸形的可用专家知识，并协助医学观察者进行正确的诊断。此外，该系统还可以研究参与决策的各种因素的影响。通过将自动诊断算法与由于异常皮层组织而导致的各种畸形的已知案例进行比较，从而对系统进行了评估。通过与已发布案例的比较和ROC分析，对系统进行了详尽的评估。

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