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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Calcium phosphate formation on porous sol-gel-derived SiO2 and CaO-P2O5-SiO2 substrates in vitro.
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Calcium phosphate formation on porous sol-gel-derived SiO2 and CaO-P2O5-SiO2 substrates in vitro.

机译：在多孔溶胶-凝胶衍生的SiO2和CaO-P2O5-SiO2基质上形成磷酸钙。

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摘要

Sol-gel-derived SiO2 and CaO-P2O5-SiO2 have been shown to be bioactive and bone bonding. In this study bioactive sol-gel-derived SiO2 and CaO-P2O5-SiO2 systems were tested for in in vitro bioactivity. The calcined ceramic monoliths were immersed in a simulated body fluid and analyzed to follow the hydroxyapatite formation on the ceramic surface. Apatite-forming ability was investigated in terms of structural changes by changing the composition and the preparation method. The role of Ca and P dopants in the substrate structure is complicated, and careful characterization is needed. The composition and structure together determine the in vitro bioactivity. The pore structure was analyzed using N2-adsorption/desorption isotherms. The results indicate that a great mesopore volume and a wide mesopore size distribution favor hydroxycarbonate apatite nucleation and a great surface area is not needed. The performed preparation process for silica in a basic environment provides a convenient way to prepare a mesoporous material. Copyright 1999 John Wiley & Sons, Inc.
机译：溶胶-凝胶衍生的SiO2和CaO-P2O5-SiO2具有生物活性和骨粘合性。在这项研究中，测试了生物活性溶胶-凝胶衍生的SiO2和CaO-P2O5-SiO2系统的体外生物活性。将煅烧的陶瓷整料浸入模拟的体液中，并进行分析以追踪在陶瓷表面上羟基磷灰石的形成。通过改变组成和制备方法，根据结构变化研究了磷灰石形成能力。 Ca和P掺杂剂在衬底结构中的作用是复杂的，并且需要仔细表征。组成和结构共同决定了体外生物活性。使用N 2吸附/解吸等温线分析孔结构。结果表明，大的中孔体积和宽的中孔尺寸分布有利于羟基碳酸盐磷灰石成核，并且不需要大的表面积。在基本环境中进行的二氧化硅的制备方法提供了制备介孔材料的方便方法。版权所有1999 John Wiley＆Sons，Inc.

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