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Organoapatite growth on an orthopedic alloy surface.

机译:骨科合金表面上的有机磷灰石生长。

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摘要

We report here a method to coat orthopedic metals with the artificial bone material organoapatite. The growth of organoapatite on titanium alloy surfaces of foils and porous cylinders involves sequential preadsorption of poly(L-lysine) and poly(L-glutamic acid) on metal, followed by exposure to organoapatite-precipitating solutions. The organoapatite characterization of the coating was carried out by transmission electron microscopy, electron diffraction, scanning electron microscopy, energy-dispersive X-ray scattering, powder X-ray diffraction, FT-IR, and elemental analysis. The preadsorbed poly(amino acids) in the form of a self-assembled bilayer of oppositely charged macromolecules can lead to a surface coverage of titanium alloy in the range of 70-90%. The deposition mechanisms could involve the surface capture of embryonic crystals and the nucleation of apatite on the bilayer. Bioabsorbable organoapatite could serve as a tissue-engineering scaffold for bone regeneration into porous implants. Copyright 1999 John Wiley & Sons, Inc.
机译:我们在这里报告了一种用人造骨材料有机磷灰石涂覆整形外科金属的方法。在箔片和多孔圆柱体的钛合金表面上有机磷灰石的生长涉及聚(L-赖氨酸)和聚(L-谷氨酸)在金属上的顺序预吸附,然后暴露于有机磷灰石沉淀溶液中。涂层的有机磷灰石表征是通过透射电子显微镜,电子衍射,扫描电子显微镜,能量色散X射线散射,粉末X射线衍射,FT-IR和元素分析进行​​的。具有相反电荷的大分子自组装双层形式的预吸附聚氨基酸可导致钛合金的表面覆盖率在70-90%的范围内。沉积机理可能涉及胚胎晶体的表面捕获和双层磷灰石的成核。可生物吸收的有机磷灰石可作为组织工程支架,用于将骨再生成多孔植入物。版权所有1999 John Wiley&Sons,Inc.

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