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HPLC analysis of dental resin composites components.

机译:牙科树脂复合材料成分的HPLC分析。

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摘要

Five uncured commercial dental resin composites (two bis-glycidyl methacrylate based products and three non-bis-glycidyl methacrylate based products) were examined for contamination with bisphenol A, which is a known xenobiotic. After the samples were processed with acetonitrile for extraction of their components, high performance liquid chromatography analysis was performed and the eluted peaks were fractionated for comparison using UV spectra. The results suggested that all the resin composites tested were contaminated with bisphenol A or its derivatives. Theoretically, bisphenol A is not a component of dental resin composite, but it could remain as an impurity of the composite during the synthesis of Bis-GMA. The results suggest that it is necessary to investigate the ability of this impurity and its derivatives in dental resin composites to cause estrogenic effects, as well as to evaluate the release of the impurity from cured resin composites. Copyright 1999 John Wiley & Sons, Inc.
机译:检查了五种未固化的商用牙科树脂复合材料(两种基于甲基丙烯酸双缩水甘油酯的产品和三种基于甲基丙烯酸非双缩水甘油酯的产品)对双酚A(一种已知的异种生物)的污染。在将样品用乙腈处理以提取其成分后,进行高效液相色谱分析,并对洗脱的峰进行分馏,以便使用UV光谱进行比较。结果表明,所有测试的树脂复合材料均被双酚A或其衍生物污染。从理论上讲,双酚A不是牙科树脂复合材料的成分,但在Bis-GMA合成过程中可能作为复合材料的杂质保留。结果表明,有必要研究该杂质及其衍生物在牙科树脂复合材料中引起雌激素作用的能力,以及评估从固化树脂复合物中释放杂质的能力。版权所有1999 John Wiley&Sons,Inc.

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