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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Use of #alpha#-tricaldum phosphate (TCP) as powders and as an aqueous dispersion to modify Processing, microstruicture, and mechanical properties of polymethylmethacrylate (PMMA) bone cements and to produce bone-substitute compounds
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Use of #alpha#-tricaldum phosphate (TCP) as powders and as an aqueous dispersion to modify Processing, microstruicture, and mechanical properties of polymethylmethacrylate (PMMA) bone cements and to produce bone-substitute compounds

机译：使用＃alpha＃-磷酸三缩醛（TCP）作为粉末和水分散体，以改性聚甲基丙烯酸甲酯（PMMA）骨水泥的加工，微结构和机械性能，并生产骨替代化合物

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摘要

Addition of tricalcium phosphate (#alpha#-TCP)powders as an aqueous dispersion to a polymethylmethacrylate(PMMA) bone cement is shown to produce a class of compositesthat due to their microstructure and mechanical properties may besuitable for application as bone substitutes. The PMMA forms asolid cellular matrix with open cells about 100 #mu#m in size andincorporating TCP clusters. The TCP aggregates inside the cellsform a porous network, with average mesopore diameters of about0.1#mu#m, that is accessible from the outer surface. If TCP isadded to PMMA in the form of dried powders, the composites arenot applicable as bone substitutes. The dynamic elastic modulus(DFM) and compressive and tensile strengths were measured anddiscussed for both classes of composites. The mechanicalproperties of the bone-substitute composites, although lower thanthe other class of composites, are still competitive with thoseproperties of a porous ceramic matrix of hydroxyapatite and withthose of natural bones.
机译：已显示将磷酸三钙（＃alpha＃-TCP）粉末作为水性分散体添加到聚甲基丙烯酸甲酯（PMMA）骨水泥中可产生一类复合材料，由于其微观结构和机械性能，它们可能适合用作骨替代品。 PMMA形成具有约100＃μm的开孔并结合TCP簇的固态细胞基质。细胞内部的TCP聚集体形成一个多孔网络，平均中孔直径约为0.1＃μm，可以从外表面进入。如果将TCP以干粉的形式添加到PMMA中，则该复合材料不能用作骨替代品。测量并讨论了两种复合材料的动弹性模量（DFM）以及抗压强度和拉伸强度。骨替代复合材料的机械性能虽然低于其他类别的复合材料，但仍与羟基磷灰石多孔陶瓷基体和天然骨的机械性能相竞争。

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