...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Fe-Au and Fe-Ag composites as candidates for biodegradable stent materials
【24h】

Fe-Au and Fe-Ag composites as candidates for biodegradable stent materials

机译：Fe-Au和Fe-Ag复合材料可作为可生物降解支架材料的候选材料

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this study, Fe-Ag and Fe-Au composites were fabricated by powder metallurgy using spark plasma sintering. Their microstructures, mechanical properties, and biocorrosion behavior were investigated by using optical microscopy, X-ray diffraction, environment scanning electronic microscopy, compressive test, electrochemical measurements, and immersion tests. Microstructure characterization indicated that the as-sintered iron-based materials obtained much finer grains than that of as-cast pure iron. Phase analysis showed that the Fe-Ag composites were composed of -Fe and pure Ag phases, and Fe-Au composites consisted of -Fe and Au phases. Compressive test showed that the improved mechanical strengths were obtained in as-sintered iron-based materials, among which the Fe-5 wt %Ag exhibited the best mechanical properties. The electrochemical and immersion tests revealed that the addition of Ag and Au could increase the corrosion rate of the iron matrix and change the corrosion mode into more uniform one. Based on the results of cytotoxicity evaluation, it was found that all the experimental material extracts performed no significant toxicity on the L-929 cells and EA. hy-926 cells, whereas a considerable inhibition on the proliferation of vascular smooth muscle cells was observed. The hemocompatibility tests showed that the hemolysis of all the experimental materials was within the range of 5%, which is the criteria value of biomaterials with good hemocomaptibility. The amount of platelet adhered on the surface of as-sintered iron-based materials was lower than that of as-cast pure iron, and the morphology of platelets kept smoothly spherical on the surface of all the experimental materials. (c) 2015 Wiley Periodicals, Inc.
机译：在这项研究中，Fe-Ag和Fe-Au复合材料是通过粉末冶金使用火花等离子体烧结制备的。通过使用光学显微镜，X射线衍射，环境扫描电子显微镜，压缩测试，电化学测量和浸没测试，研究了它们的微观结构，力学性能和生物腐蚀行为。显微组织表征表明，烧结态铁基材料比铸态纯铁获得更细的晶粒。相分析表明，Fe-Ag复合材料由-Fe和纯Ag相组成，Fe-Au复合材料由-Fe和Au相组成。压缩试验表明，在烧结的铁基材料中获得了提高的机械强度，其中Fe-5wt％Ag表现出最佳的机械性能。电化学和浸没测试表明，添加Ag和Au可以提高铁基体的腐蚀速率，并将腐蚀方式改变为更均匀的腐蚀方式。根据细胞毒性评估的结果，发现所有实验材料提取物对L-929细胞和EA均无明显毒性。 hy-926细胞，而对血管平滑肌细胞的增殖有相当大的抑制作用。血液相容性测试表明，所有实验材料的溶血均在5％范围内，这是具有良好血液相容性的生物材料的标准值。烧结态铁基材料表面的血小板附着量低于铸态纯铁，并且所有实验材料表面的血小板形态均保持光滑球形。 （c）2015年威利期刊有限公司

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号