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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Biocompatibility of electroactive polymers in tissues
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Biocompatibility of electroactive polymers in tissues

机译：电活性聚合物在组织中的生物相容性

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The biocompatibility of ethylene-vinyl acetate copolymer (EVAc), polyethylene (PE), and polyaniline (PANi) films in the emeraldine (EM), nigraniline (NA) and leucoemeraldine (LM) intrinsic oxidation states were assessed through subcutaneous implantation into male Sprague-Dawley rats beneath the dorsal skin, for a period ranging from 19 to 90 weeks. Histological examination, interstitial pressure measurement, and X-ray photoelectron spectroscopy (XPS) were employed to determine the biocompatibility of the polymers. The polymers did not provoke inflammatory responses in the subcutaneous tissues over the entire implantation period. Characteristics features associated with tissue-implant incompatibility were not evident near the implantation. Interstitial pressure was mea-sured to evaluate the development of tissue. Low interstitial pressure readings on the region of implantation confirmed the biocompatibility of these polymer types. The surface composition of the electroactive aniline polymers before and after the implantation was characterized by XPS.
机译：通过皮下植入雄性Sprague来评估乙烯-乙酸乙烯酯共聚物（EVAc），聚乙烯（PE）和聚苯胺（PANi）膜在翡翠（EM），黑肾上腺素（NA）和白细胞翡翠（LM）固有氧化态中的生物相容性-Dawley大鼠位于背部皮肤下方，持续19至90周。组织学检查，间隙压力测量和X射线光电子能谱（XPS）用于确定聚合物的生物相容性。在整个植入期间，该聚合物不会在皮下组织中引起炎症反应。与组织-植入物不相容性相关的特征在植入附近并不明显。测量间质压以评估组织的发育。植入区域的低间隙压力读数证实了这些聚合物类型的生物相容性。 XPS表征了植入前后电活性苯胺聚合物的表面组成。

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