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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Juniper wood as a possible implant material
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Juniper wood as a possible implant material

机译：木可能是植入材料

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摘要

Natural materials, such as wood and bone, possess structures fulfilling the requirements of support and transport of nutrients. Similarity in function and properties provides inspiration for investigating the possible use of wood as an implant material. Juniperus communis wood is dense, durable, and strong and has naturally impregnated essential oils that display antiseptic properties. This study investigated the toxicity of the oil, the effect of sterilization on the mechanical properties of the wood, and bone attachment with animal studies. The possible toxicity of the oil was determined orally and by intravenous injection. At low concentrations, the dose that would be released by the wood in the body could be tolerated without any detrimental effects. Sterilization of the wood in boiling water lowered the elastic modulus and modulus of rupture to a level at which the elastic modulus could be better matched to bone. Wood shaped into the form of femoral implants were implanted into rabbits and displayed good acceptance by the body up to a period of 3 years, indicating bone apposition, abutment into pores, and growth into drilled cavities.
机译：天然材料，例如木头和骨头，具有满足营养和支持营养需求的结构。功能和特性的相似性为研究将木材用作植入材料的可能性提供了启发。杜松木是致密，耐用和坚固的，具有自然浸渍的精油，具有防腐性能。这项研究通过动物实验研究了油的毒性，灭菌对木材机械性能的影响以及骨骼附着的影响。该油可能的毒性是通过口服和静脉注射确定的。在低浓度下，可以忍受木材在体内释放的剂量，而不会产生任何有害影响。木材在沸水中的灭菌将弹性模量和断裂模量降低到了弹性模量可以更好地与骨骼匹配的水平。将形状为股骨植入物的木材植入兔子体内，并在长达3年的时间里显示出良好的身体接受性，表明骨骼并置，邻接到毛孔中以及生长到钻孔中。

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