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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Wear Evaluation of Cobalt-Chromium Alloy for Use in a Metal-on-Metal Hip Prosthesis
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Wear Evaluation of Cobalt-Chromium Alloy for Use in a Metal-on-Metal Hip Prosthesis

机译：用于金属对金属髋关节假体的钴铬合金的磨损评估

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Wear of the polyethylene in total joint prostheses has been a source of morbidity and early device failure, which has been extensively reported in the last 20 years. Although research continues to attempt to reduce the wear of polyethylene joint-bearing surfaces by modifications in polymer processing, there is a renewed interest in the use of metal-on-metal bearing couples for hip prostheses. Wear testing of total hip replacement systems involving the couple of metal or ceramic heads on polymeric acetabular components has been performed and reported, but, until recently, there has been little data published for pin-on-disk or hip-simulator wear studies involving the combination of a metallic femoral head component with an acetabular cup composed of the same or a dissimilar metal. This study investigated the in vitro wear resistance of two cobalt/chromium/molybdenum alloys, which differed primarily in the carbon content, as potential alloys for use in a metal-on-metal hip-bearing couple. The results of pin-on-disk testing showed that the alloy with the higher (0.25 percent) carbon content was more wear resistant, and this alloy was therefore chosen for testing in a hip-simulator system, which modeled the loads and motions that might be exerted clinically. Comparison of the results of metal-on-polyethylene samples to metal-on-metal samples showed that the volumetric wear of the metal-on-polyethylene bearing couple after 5,000,000 cycles was 110-180 times that for the metal-bearing couple. Polyethylene and metal particles retrieved from either the lubricant for pin-on-disk testing or hip simulator testing were characterized and compared with particles retrieved from periprosthetic tissues by other researchers, and found to be similar. Based upon the results of this study, metal-on-metal hip prostheses manufactured from the high carbon cobalt/chromium alloy that was investigated hold sufficient promise to justify human clinical trials.
机译：全关节假体中聚乙烯的磨损已成为发病率和早期器械故障的根源，在过去的20年中已广泛报道。尽管研究继续试图通过改变聚合物加工工艺来减少聚乙烯关节轴承表面的磨损，但人们对将金属对金属轴承对用于髋关节假体重新产生了兴趣。已经进行了并报道了涉及在聚合髋臼组件上使用金属或陶瓷头对的全髋关节置换系统的磨损测试，但是直到最近，有关椎间盘或髋关节模拟器磨损研究的数据很少公布。金属股骨头组件与由相同或不同金属组成的髋臼杯的组合。这项研究调查了两种钴/铬/钼合金的体外耐磨性，这两种钴/铬/钼合金的主要含碳量不同，它们是用于金属对金属髋关节轴承的潜在合金。针在磁盘上的测试结果表明，碳含量较高（0.25％）的合金具有更高的耐磨性，因此，该合金被选作髋关节模拟器系统中的测试对象，该系统模拟了可能产生的载荷和运动。在临床上发挥作用。将金属对聚乙烯样品与金属对金属样品的结果进行比较，结果表明，在5,000,000次循环后，聚乙烯对金属轴承偶的体积磨损是金属对偶的体积磨损的110-180倍。表征了从润滑剂中回收的用于销盘测试或髋部模拟器测试的聚乙烯和金属颗粒，并将其与其他研究人员从假体周围组织回收的颗粒进行了比较，发现相似。根据这项研究的结果，由高碳钴/铬合金制成的金属对金属髋关节假体具有充分的前景可用于人体临床试验。

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