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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Augmentation of implant purchase with bone cements: an in vitro study of injectability and dough distribution.
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Augmentation of implant purchase with bone cements: an in vitro study of injectability and dough distribution.

机译：用骨水泥增强植入物购买：可注射性和面团分布的体外研究。

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Vertebroplasty is widely used to treat (augment) osteoporotic fractures of the spine. This technique--with or without metallic implants--might have more widespread indications, if the mechanics of the injection and distribution of the cement dough through cannulated instruments and implants were better understood. This study was performed to investigate injectability of calcium phosphate and acrylic bone cements through implant prototypes, which featured different perforated sleeve designs. Using a custom-made capillary rheometer, the forces needed to inject 10 mL of the cement dough through standard cannulas were measured in the first series of experiments. In the second series, plastic sleeves were attached to the rheometer, simulating the implant. In both series, the dough was injected into ambient laboratory atmosphere, and in the second series, cement distribution was analyzed by means of an optical system. Injection of cement dough through the cannulas required forces between 50 and 400 N in the case of acrylic cements and between 40 and 500 N in case of the calcium phosphate cements. Using different sleeves did not have a significant influence on the distribution of the cement dough around the sleeve. The amount of cement dough injected was reduced when a perforated implant was attached to the cannula. More material was delivered through the proximal holes of the implant, leading to a V-shaped distribution of the cement dough. Among topics to be investigated in future studies is determination of the injectability of cement dough into trabecular bone or bone-like structures.
机译：椎体成形术广泛用于治疗（增强）脊柱骨质疏松性骨折。如果可以更好地理解通过空心器械和植入物进行水泥生面团的注入和分配的力学原理，则无论有无金属植入物，该技术都有更广泛的应用前景。进行这项研究的目的是通过植入物原型研究磷酸钙和丙烯酸骨水泥的可注射性，该原型具有不同的穿孔套筒设计。使用定制的毛细管流变仪，在第一批实验中测量了通过标准套管注入10 mL水泥生面团所需的力。在第二系列中，将塑料套管连接到流变仪上，模拟植入物。在两个系列中，将面团注入实验室环境中，在第二个系列中，通过光学系统分析水泥的分布。通过套管注入水泥生面团，在丙烯酸水泥的情况下需要50到400 N，在磷酸钙水泥的情况下需要40到500N。使用不同的套筒对水泥生面团在套筒周围的分布没有显着影响。当将穿孔的植入物附接到套管时，注入的水泥生面团的量减少。更多的材料通过植入物的近端孔输送，导致水泥面团呈V形分布。在将来的研究中要研究的课题之一是确定水泥生面团注入小梁骨或类骨结构的可注射性。

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