Biocompatibility and Antibacterial Activity Studies of Polyamidoamine (PAMAM) Dendron, Side Chain Dendritic Oligourethane (SCDOU)

S. Ghosh; A. K. Banthia

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Biocompatibility and Antibacterial Activity Studies of Polyamidoamine (PAMAM) Dendron, Side Chain Dendritic Oligourethane (SCDOU)

机译：聚酰胺（PAMAM）树突状，侧链树状低聚乙烷（SCDOU）的生物相容性和抗菌活性研究

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Cytotoxicity of both polyamidoamine dendritic diol (PAMAM) and side chain dendritic oligourethane (SC-DOU) was studied through interaction with mammalian fibroblast cells (L929). Cell metabolic activity in the presence of dendritic polymers was measured using an MTT assay exhibiting significant cell viability. Additionally, the antibacterial activity of PAMAM dendron, SCDOU, as well as their silver-doped structures was studied against Escherichia coli bacteria. The results showed that the silver-doped structures attain high antibacterial activity. Formation of silver-doped dendritic polymers was investigated from the UV-visible plasmon absorption band of silver particles.

机译：通过与哺乳动物成纤维细胞（L929）的相互作用，研究了聚酰胺基胺树枝状二醇（PAMAM）和侧链树枝状低聚乙烷（SC-DOU）的细胞毒性。使用表现出显着细胞活力的MTT测定法测量在树突状聚合物存在下的细胞代谢活性。此外，还研究了PAMAM树突，SCDOU及其掺杂银的结构对大肠杆菌的抗菌活性。结果表明，银掺杂结构具有较高的抗菌活性。从银颗粒的紫外可见等离子体吸收带研究了掺杂银的树枝状聚合物的形成。

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《Journal of biomedical materials research. Part B, Applied biomaterials.》 |2004年第1期|共5页
作者
S. Ghosh; A. K. Banthia;
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正文语种 eng
中图分类医用一般科学;
关键词
polyamidoamine (PAMAM); side chain dendritic oligourethane (SCDOU); cytotoxicity; antibacterial;

机译：聚酰胺胺（PAMAM）;侧链树状低聚乙烷（SCDOU）;细胞毒性;抗菌;

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1. Biocompatibility and Antibacterial Activity Studies of Polyamidoamine (PAMAM) Dendron, Side Chain Dendritic Oligourethane (SCDOU) [J] . S. Ghosh, A. K. Banthia Journal of biomedical materials research. Part B, Applied biomaterials. . 2004,第1期

机译：聚酰胺（PAMAM）树突状，侧链树状低聚乙烷（SCDOU）的生物相容性和抗菌活性研究
2. Synthesis of novel polyamidoamine (PAMAM) side chain dendritic oligourethane architecture [J] . Samaresh Ghosh, Ajit K. Banthia Polymer bulletin . 2001,第2期

机译：新型聚酰胺基胺（PAMAM）侧链树状低聚乙烷结构的合成
3. Synthesis of novel polyamidoamine (PAMAM) side chain dendritic oligourethane architecture [J] . Samaresh Ghosh, Ajit K. Banthia Polymer Bulletin . 2001,第2期

机译：新型聚酰胺基胺（PAMAM）侧链树状低聚乙烷结构的合成
4. ASSEMBLY OF LAYER-BY-LAYER FILMS OF MYOGLOBIN (Mb) AND GOLD NANOPARTICLES ENCAPSULATED INSIDE POLYAMIDOAMINE (PAMAM) DENDRIMERS:AN ELECTROCHEMICAL STUDY [C] . Hong ZHANG, Naifei HU The 12th International Beijing Conference and Exhibition on Instrumental Analysis : Conference Abstracts . 2007

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5. N-thiolated beta-lactams: Influence of the lipophilic tricarbon side chain character on antibacterial and anticancer activity and studies on detoxifying polyacrylated nanoparticles for delivering antibiotics [D] . Garay Jimenez, Julio Cesar 2008

机译：N-硫醇化的β-内酰胺类化合物：亲脂性三碳侧链特性对抗菌和抗癌活性的影响以及对用于释放抗生素的聚丙烯酸酯化纳米颗粒进行解毒的研究
6. Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo [O] . Yanna Zhao, Yifei Guo, Ran Li, -1

机译：用聚酰胺酰胺（PAMAM）和低聚乙二醇（OEG）树枝蛋白的Codendrimer制备的甲氨蝶呤纳米颗粒：体外和体内抗肿瘤功效
7. Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo [O] . Yanna Zhao, Yifei Guo, Ran Li, 2016

机译：用聚酰胺胺（PAMAM）和寡核苷酸（OEG）树枝状甲醛（OEG）DENDRONS的CODENDENDENDRIMER制备甲氨蝶呤纳米粒子：体外和体内抗肿瘤效力

Biocompatibility and Antibacterial Activity Studies of Polyamidoamine (PAMAM) Dendron, Side Chain Dendritic Oligourethane (SCDOU)

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