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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Biomimetic apatite coatings on titanium coprecipitated with cephradine and salviae miltlorrhizae.
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Biomimetic apatite coatings on titanium coprecipitated with cephradine and salviae miltlorrhizae.

机译：钛上的仿生磷灰石涂层与头孢拉定和丹参的共沉淀物。

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摘要

Incorporation of antibiotics in the apatite coatings on titanium surface is an effective step for surgical infections of titanium implant. In this work, antibiotics cephradine and traditional Chinese medicine salviae miltlorrhizae (SM) were incorporated in the simulated body fluid (SBF). The apatite coatings were coprecipitated with cephradine and SM by a biomimetic method. The research showed that in the biomimetic coprecipitation process cephradine containing carboxylic groups were beneficial to the apatite coprecipitation. X-ray diffraction patterns showed that cephradine had a positive effect on the crystal growth in terms of cystallinity. And also in the Fourier transformed infrared spectra, the organic groups corresponded with cephradine were also observed. However, little apatite formed on the titanium immersed in SBF with SM. Probably, SM was more absorbed on the surface when calcium and phosphate ions precipitated.
机译：在钛表面磷灰石涂层中掺入抗生​​素是对钛植入物进行外科手术感染的有效步骤。在这项工作中，将头孢拉定抗生素和中药丹参（SM）掺入模拟体液（SBF）中。通过仿生方法将磷灰石涂层与头孢拉定和SM共沉淀。研究表明，在仿生共沉淀过程中，含羧基的头孢拉定对磷灰石的共沉淀是有益的。 X射线衍射图谱显示，头孢拉定对晶体的结晶度有积极作用。并且在傅立叶变换的红外光谱中，还观察到与头孢拉定对应的有机基团。但是，浸入SM的SBF中的钛上几乎没有形成磷灰石。当钙和磷酸根离子沉淀时，SM可能更多地吸附在表面上。

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