...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Study on the lubrication mechanism of natural joints by confocal laser scanning microscopy
【24h】

Study on the lubrication mechanism of natural joints by confocal laser scanning microscopy

机译：共聚焦激光扫描显微镜研究天然关节的润滑机理

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Natural joints have an excellent lubricating function, but the detailed mechanism is still unclear. To clarify this lubricating mechanism, we observed the behavior of the cartilage surface under the physiological loading condition with confocal laser scanning microscopy in normal and osteoarthritis (OA) cartilage rabbit specimens. Even with a considerable loading condition, in both natural and OA cartilage, the fluid pool area coexisted with the direct contact area. In the junction from the direct contact area to the fluid area, there was a third area with a liquid-crystal arrangement. In OA cartilage, these areas were generally irregular and small. These results suggest that a lubrication system in the fluid phase, such as squeeze film lubrication, might work under severe pressure in normal cartilage, and hyaluronic acid macromolecules in the synovial fluid might form a liquid-crystal structure and support pressure on the cartilage surface, whereas these systems did not affect the OA cartilage.
机译：天然接头具有出色的润滑功能，但具体机理尚不清楚。为了阐明这种润滑机理，我们用共聚焦激光扫描显微镜观察了正常和骨关节炎（OA）软骨兔标本中在生理负荷条件下软骨表面的行为。即使在自然和OA软骨的负荷条件相当大的情况下，流体池区域也与直接接触区域共存。在从直接接触区域到流体区域的接合处，存在具有液晶排列的第三区域。在骨关节炎软骨中，这些区域通常不规则且很小。这些结果表明，流体相的润滑系统（例如挤压膜润滑）可能在正常的软骨中承受巨大的压力，而滑液中的透明质酸大分子可能会形成液晶结构并在软骨表面上支撑压力，这些系统并没有影响OA软骨。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号