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首页> 外文期刊>Journal of Biomolecular Structure and Dynamics >One-parameter discrete model of the genetic diversity.
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One-parameter discrete model of the genetic diversity.

机译:遗传多样性的一参数离散模型。

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摘要

One-parameter discrete model estimating genetic distance between precursor and descendant nucleotide sequences after several steps of substitution acts is developed. This model based on the previously introduced symbol sequences enumeration procedure (M.Y. Shchelkanov, A.N. Yudin, A.V. Antonov, N.S. Starikov, A.A. Vedenov, E.V. Karamov, J. Biomol. Struct. Dyn. 15, 231-241 (1997)) differs from Jukes-Cantor and Kimura models by the absence of the assumptions usual for continuous Markov's processes. Formula obtained with the help of our model are more preferable since they take into account multiple repetition substitution ability and they are correct in the entire admissible range of parameters.
机译:建立了一个参数离散模型,该模型估计了几步取代后的前体和后代核苷酸序列之间的遗传距离。该模型基于先前介绍的符号序列枚举过程(MY Shchelkanov,AN Yudin,AV Antonov,NS Starikov,AA Vedenov,EV Karamov,J。Biomol。Struct。Dyn。15、231-241(1997))不同于Jukes -Cantor和Kimura模型缺乏连续马尔可夫过程的通常假设。借助我们的模型获得的公式更为可取,因为它们考虑了多次重复替换能力,并且在整个参数允许范围内都是正确的。

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