Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.

Liu M; Yang L; Deng W; Su M; Wang C; Lin SB; Kan LS; Bai C

首页> 外文期刊>Journal of Biomolecular Structure and Dynamics >Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.

【24h】

Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.

机译：5-溴胞嘧啶的选择性取代对DNA三重螺旋构象的影响。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Three triplex DNAs containing 5-bromocytosine[BrC] were studied by vibrational spectroscopy and molecular modelling. Firstly, three oligodeoxypyrimidines of 5'-(TC)3-T4-(BrCT)3 [CBrC], 5'-(TBrC)3-T4-(CT)3 [BrCC] and 5'-(TBrC)3-T4-(BrCT)3 [BrCBrC] were synthesized and then reacted with an oligodeoxypurine of 5'-(AG)3 at pH=4.5 in phosphate buffer respectively to form three comparative hairpin triplex named CY,YC and YY. The results of FT-Raman and IR revealed that YY is almost in A-like form, CY and YC are combinations of A-like form and B-like form, but A-form dominates in CY while B-form is equivalent as A-form in YC. The result is consistent with the theoretical analysis.

机译：通过振动光谱和分子模拟研究了三个含有5-溴胞嘧啶[BrC]的三链体DNA。首先，三个5'-（TC）3-T4-（BrCT）3 [CBrC]，5'-（TBrC）3-T4-（CT）3 [BrCC]和5'-（TBrC）3-T4的寡脱氧嘧啶合成-（BrCT）3 [BrCBrC]，然后在磷酸盐缓冲液中与pH'= 4.5的5'-（AG）3寡脱氧嘌呤反应，分别形成三个比较的发夹三元体CY，YC和YY。 FT-Raman和IR的结果表明，YY几乎是A样形式，CY和YC是A样形式和B样形式的组合，但CY中A形式占优势，而B形式与A相当。 -YC中的表格。结果与理论分析相符。

著录项

来源
《Journal of Biomolecular Structure and Dynamics》 |1998年第5期|共9页
作者
Liu M; Yang L; Deng W; Su M; Wang C; Lin SB; Kan LS; Bai C;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类分子生物学;
关键词
Cytosine; DNA; Models; Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; 胞嘧啶; 模型; 分子; 核酸构象; 寡脱氧核糖核苷酸类;

机译：Cytosine;DNA;Models;Molecular;Nucleic Acid Conformation;Oligodeoxyribonucleotides;胞嘧啶;模型;分子;核酸构象;寡脱氧核糖核苷酸类;

相似文献

外文文献
中文文献
专利

1. Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices. [J] . Liu M, Yang L, Deng W, Journal of Biomolecular Structure and Dynamics . 1998,第5期

机译：5-溴胞嘧啶的选择性取代对DNA三重螺旋构象的影响。
2. Thermodynamics of the melting of PNA(2)/DNA triple helices. [J] . Krupnik OV, Guscho Y, Sluchanko K, Journal of Biomolecular Structure and Dynamics . 2001,第3期

机译：PNA（2）/ DNA三重螺旋融化的热力学。
3. Synthesis and monitored selection of nucleotide surrogates for binding T:A base pairs in homopurine-homopyrimidine DNA triple helices. [J] . Mokhir AA, Connors WH, Richert C Nucleic Acids Research . 2001,第17期

机译：用于合成高嘌呤-高嘧啶DNA三螺旋中结合T：A碱基对的核苷酸替代物的合成和监测选择。
4. Determining Rotational Conformations of Substituted DNA Sequences On the Nucleosome Core Particle [C] . A. Levi Pierce, B. Terry Clark International Conference on Modeling, Simulation and Visualization Methods . 2008

机译：确定核心核心颗粒上取代的DNA序列的旋转构型
5. Physical chemistry of nucleic acid triple helices. [D] . Roberts, Richard William. 1993

机译：核酸三螺旋的物理化学。
6. Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices. [O] . A A Moraru-Allen, S Cassidy, J L Asensio Alvarez, 1997

机译：Coralyne偏爱分子内DNA三重螺旋中TA.T三重之间的插入。
7. Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices. [O] . Moraru-Allen, A A, Cassidy, S, Asensio Alvarez, J L, 1997

机译：Coralyne偏爱分子内DNA三重螺旋中TA.T三重之间的插入。

Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.

摘要

著录项

相似文献

相关主题

期刊订阅