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首页> 外文期刊>Journal of bronchology: dedicated to the art and science of bronchoscopy and related disciplines >Clinically Relevant Information Obtained by Performing Autofluorescence Bronchoscopy
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Clinically Relevant Information Obtained by Performing Autofluorescence Bronchoscopy

机译：通过执行自动荧光支气管镜检查获得的临床相关信息

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摘要

The purpose of the study was to examine the clinically relevant findings that were obtained only by autofluorescence bronchoscopy and not by white-light bronchoscopy. Data from patients at risk for lung cancer who underwent both white-light bronchoscopy and autofluorescence bronchoscopy were analyzed on a per-patient and on a per-bronchoscopy base. Clinically relevant findings were defined as follows: (1) histo-logic examination of bronchial biopsy specimen showing moderate dysplasia, severe dysplasia, or carcinoma in situ; (2) assessment by the bronchoscopist that the bronchial area to be treated endoscopically was better visualized by autofluorescence bronchoscopy, which was of influence on the treatment. A total of 224 bronchoscopies were performed in 114 patients. Endobronchial therapy was performed during 26 of these bronchoscopies. Clinical relevant findings resulted from 28 autofluorescence bronchoscopies in 18 patients. Twenty-five of 101 intraepithelial neoplastic lesions were detected by autofluorescence bronchoscopy alone during 18 bronchoscopies in 14 patients. During 10 bronchoscopies in 9 patients, autofluorescence bronchoscopy resulted in a better visualization of the extent of endobronchial spread of tumor, which subsequently was treated with endobronchial therapy. We concluded that by adding autofluorescence bronchoscopy to white-light bronchoscopy, clinically relevant information was obtained in 13% (28 of 223) of the bronchoscopies and in 16% (18 of 114) of the patients.
机译：该研究的目的是检查仅通过自发荧光支气管镜检查而非白光支气管镜检查获得的临床相关发现。在每个患者和每个支气管镜的基础上分析了接受白光支气管镜检查和自发荧光支气管镜检查的有肺癌风险的患者的数据。与临床相关的发现定义如下：（1）支气管活检标本的组织学检查显示为中度异常增生，严重异常增生或原位癌。 （2）由支气管镜医师评估，通过自发荧光支气管镜可以更好地看到内镜下待治疗的支气管区域，这对治疗有影响。 114名患者共进行了224次支气管镜检查。这些支气管镜检查中有26例进行了支气管内治疗。临床相关发现来自18例患者的28例自发荧光支气管镜检查。在14例患者的18例支气管镜检查中，仅通过自身荧光支气管镜检查就发现了101例上皮内肿瘤病变中的25例。在9例患者的10次支气管镜检查中，自体荧光支气管镜检查可以更好地可视化肿瘤在支气管内的扩散程度，随后对其进行支气管内治疗。我们得出的结论是，将自体荧光支气管镜添加到白光支气管镜中，在13％（223例中的28例）和16％（114例中的18例）患者中获得了临床相关信息。

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