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Toward portable breath acetone analysis for diabetes detection

机译:走向便携式呼吸丙酮分析以检测糖尿病

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摘要

Diabetes is a lifelong condition that may cause death and seriously affects the quality of life of a rapidly growing number of individuals. Acetone is a selective breath marker for diabetes that may contribute to the monitoring of related metabolic disorder and thus simplify the management of this illness. Here, the overall performance of Si-doped WO_3 nanoparticles, made by flame spray pyrolysis, as portable acetone detectors is critically reviewed focusing on the requirements for medical diagnostics. The effect of flow rate, chamber volume and acetone dissociation within the measuring chamber is discussed with respect to the calibration of the sensor response. The challenges for the fabrication of portable breath acetone sensors based on chemo-resistive detectors are underlined indicating possible solutions and novel research directions.
机译:糖尿病是可能导致死亡并严重影响迅速增长的个体生活质量的终生疾病。丙酮是糖尿病的选择性呼吸标志物,可能有助于监测相关的代谢紊乱,从而简化该病的治疗。在这里,着重回顾了医学诊断要求,对通过火焰喷雾热解法制成的掺硅WO_3纳米颗粒作为便携式丙酮检测器的总体性能进行了严格审查。相对于传感器响应的校准,讨论了测量室内流速,腔室体积和丙酮离解的影响。强调了基于化学抗性检测器的便携式呼吸丙酮传感器的制造挑战,指出了可能的解决方案和新颖的研究方向。

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