Electrical and hemodynamic correlates of the maximal rate of pressure increase in the human left ventricle.

Fried AG; Parker AB; Newton GE; Parker JD

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Electrical and hemodynamic correlates of the maximal rate of pressure increase in the human left ventricle.

机译：人体左心室最大压力增加率的电学和血液动力学相关性。

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BACKGROUND: The rate of left ventricular (LV) pressure increase (LV + dP/dt) may be related to QRS duration, as well as to a number of hemodynamic parameters. METHODS AND RESULTS: We studied the relation between basal LV + dP/dt and QRS duration in 43 patients with normal LV function and 81 patients with heart failure undergoing diagnostic catheterization. We also examined the relationship between LV + dP/dt and heart rate, as well as measures of both LV preload and afterload. In patients with normal LV function, there was a strong relationship between basal LV + dP/dt and resting heart rate, whereas the relationship with QRS duration was of borderline significance. In patients with heart failure, the relationship with heart rate was lost; however, LV systolic pressure, QRS duration, and LV end-diastolic pressure all made significant contributions to a model predicting LV + dP/dt. CONCLUSIONS: These data show a strong relationship between resting heart rate and LV + dP/dt in the healthy human LV. In patients with heart failure, the relationship with heart rate is not maintained; however, there is a systematic relationship between LV + dP/dt and both the time-course of the electrical activation and measures of LV loading conditions.

机译：背景：左心室（LV）压力增加率（LV + dP / dt）可能与QRS持续时间以及许多血液动力学参数有关。方法和结果：我们研究了43例LV功能正常的患者和81例心力衰竭的诊断性导管插入术的基础LV + dP / dt与QRS持续时间的关系。我们还检查了LV + dP / dt与心率之间的关系，以及LV前负荷和后负荷的测量方法。 LV功能正常的患者，基础LV + dP / dt与静息心率之间有很强的关系，而与QRS持续时间的关系则具有临界意义。心力衰竭患者失去与心率的关系;然而，LV收缩压，QRS持续时间和LV舒张末期压均对预测LV + dP / dt的模型做出了重要贡献。结论：这些数据表明健康人左心室静息心率与左心室LV + dP / dt有很强的关系。心力衰竭患者无法维持与心率的关系;但是，LV + dP / dt与电激活的时间过程以及LV负载条件的度量之间存在系统的关系。

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《Journal of cardiac failure》 |1999年第1期|共9页
作者
Fried AG; Parker AB; Newton GE; Parker JD;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Heart Conduction System; Ventricular Function; Left; 心脏传导系统; 心室功能; 左;

机译：Heart Conduction System;Ventricular Function;Left;心脏传导系统;心室功能;左;

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1. Electrical and hemodynamic correlates of the maximal rate of pressure increase in the human left ventricle. [J] . Fried AG, Parker AB, Newton GE, Journal of cardiac failure . 1999,第1期

机译：人体左心室最大压力增加率的电学和血液动力学相关性。
2. Electrical and hemodynamic correlates of the maximal rate of pressure increase in the human left ventricle. [J] . Fried AG, Parker AB, Newton GE, Journal of cardiac failure . 1999,第1期

机译：人体左心室最大压力增加率的电学和血液动力学相关性。
3. Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans. [J] . Thornton JudithM, Aziz Tipu, Schlugman David, The Journal of Physiology . 2002,第Pta2期

机译：中脑的电刺激会增加清醒的人的心率和动脉血压。
4. Hemodynamic and Left Ventricular Pressure-Volume Responses to Counterpulsation in Mock Circulation and Acute Large Animal Models [C] . Koenig S.C., Pantalos G.M., Litwak K.N., Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE . -1

机译：在模拟循环和急性大动物模型中对反搏的血流动力学和左心室压力反应
5. Hemodynamic Changes during Contrast Injections in Cerebral Angiography: Effects on Intra-aneurysmal Pressures and Extraction of Arterial Blood Flow Rates [D] . Marfoglio, Samantha. 2020

机译：脑血管造影中对比注射期间的血流动力学变化：对动脉内部压力的影响和动脉血流率的提取
6. Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans [O] . Judith M Thornton, Tipu Aziz, David Schlugman, 2002

机译：中脑的电刺激会增加清醒的人的心率和动脉血压
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Electrical and hemodynamic correlates of the maximal rate of pressure increase in the human left ventricle.

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