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首页> 外文期刊>Journal of cardiac surgery. >Results of aortic arch repair with hypothermic circulatory arrest and retrograde cerebral perfusion.
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Results of aortic arch repair with hypothermic circulatory arrest and retrograde cerebral perfusion.

机译:低温循环停止和逆行脑灌注修复主动脉弓的结果。

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BACKGROUND: Repair of aortic arch pathology is reliably performed with hypothermic circulatory arrest, but the best method of brain protection is controversial. METHODS: We reviewed a consecutive series of 67 patients who had aortic arch repair with hypothermic circulatory arrest. Retrograde perfusion of arterial blood into the superior vena cava (SVC) during systemic arrest was used in 87%. Average age was 65 years. Acute dissection was present in 25%. Average circulatory arrest time was 37 minutes, and average temperature 17.7 degrees C. RESULTS: Hospital mortality was 1.5%. Strokes occurred in 4.5%. Temporary neurological dysfunction occurred in 16%. Multivariate logistic regression analysis showed that acute dissection was the only independent predictor of the combined risk of stroke and temporary neurological dysfunction (odds ratio 8.5). Duration of circulatory arrest and patient age were not risk factors for adverse neurological outcome. CONCLUSION: Continuous arterial perfusion of the SVC during hypothermic circulatory arrest provides excellent cerebral protection for aortic arch repair. Acute dissection is an independent risk factor for adverse neurological outcome. Arrest time is not a predictor of neurological dysfunction.
机译:背景:主动脉弓病变的修复可通过低温循环性阻滞可靠地进行,但脑部保护的最佳方法仍存在争议。方法:我们回顾了67例行主动脉弓修补术并伴有低温循环停止的患者。全身停搏期间向上腔静脉(SVC)逆行灌注动脉血的比例为87%。平均年龄为65岁。急性解剖的比例为25%。平均循环停止时间为37分钟,平均温度为17.7摄氏度。结果:医院死亡率为1.5%。中风发生率为4.5%。发生暂时性神经功能障碍的比例为16%。多元逻辑回归分析表明,急性解剖是中风和暂时性神经功能障碍合并风险的唯一独立预测因子(优势比为8.5)。循环骤停的持续时间和患者年龄不是不良神经学预后的危险因素。结论:在低温循环停止期间,SVC的持续动脉灌注为主动脉弓修复提供了出色的大脑保护。急性解剖是不良神经系统预后的独立危险因素。逮捕时间不是神经系统功能障碍的预测指标。

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