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首页> 外文期刊>Journal of cardiac surgery. >CABG without using heparin in a patient with heparin-induced thrombocytopenia.
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CABG without using heparin in a patient with heparin-induced thrombocytopenia.

机译：肝素诱导的血小板减少症患者不使用肝素的CABG。

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BACKGROUND: Despite the low incidence of heparin-induced thrombocytopenia and thrombosis, these two syndromes are much disputed in life-threatening conditions especially in cardiovascular surgery where heparin is routinely used. Nowadays a pharmacological agent that can exactly replace heparin does not exist. Many of the drugs called "alternative drugs to heparin" are associated with a high risk of hemorrhagic complications and an increased need of blood transfusions. Neither the use of heparin nor "alternative drugs to heparin" may be the best way to revascularize a patient with heparin-induced thrombocytopenia. METHODS: Coronary artery bypass grafting without using heparin was performed in a 62-year-old male patient with heparin-induced thrombocytopenia. He received clopidogrel and acethyl salicylic acid for 2 days before operation. He was operated off-pump using special maneuvers. RESULTS: He was discharged on postoperative day 5 after an uneventful course and is doing well in the sixth month postoperatively. CONCLUSIONS: According to our investigations in English literature, this surgical technique and coronary artery bypass grafting without using heparin is firstly described in this article. Increasing the number of cases will show the reliability and safety of this method.
机译：背景：尽管肝素诱发的血小板减少症和血栓形成的发生率较低，但在威胁生命的情况下，尤其是在常规使用肝素的心血管外科手术中，这两种综合征存在很大争议。如今，不存在可以完全替代肝素的药理剂。许多被称为“肝素替代药物”的药物与出血并发症的高风险和输血的需求增加有关。肝素或“肝素替代药物”的使用都不是使肝素诱导的血小板减少症患者血运重建的最佳方法。方法：对一名62岁男性肝素诱发的血小板减少症患者进行了不使用肝素的冠状动脉搭桥术。术前2天接受氯吡格雷和乙基水杨酸治疗。他通过特殊的演习在场外被操纵。结果：他在病情平稳后的术后第5天出院，并且在术后的第6个月状况良好。结论：根据我们在英国文献中的调查，本文首先介绍了这种手术技术和不使用肝素的冠状动脉搭桥术。案件数量的增加将证明这种方法的可靠性和安全性。

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