Ochronosis and aortic valve stenosis.

Butany JW; Naseemuddin A; Moshkowitz Y; Nair V

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Ochronosis and aortic valve stenosis.

机译：骨质疏松症和主动脉瓣狭窄。

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Valvular heart disease has numerous etiologies. These range from congenital malformations to infectious and degenerative diseases. Clinically, these result in significant problems, the management of which can necessitate valve replacement with prosthetic heart valves. A rare cause is the deposition of foreign material in the valvular tissues, and these include inborn errors of metabolism of the essential amino acids. Alkaptonuria, an autosomal recessive trait, can result in the accumulation of excess homogentisic acid. This can manifest as pigmentation in the skin and other tissues, including heart valves. Accumulation of this pigment can lead to an inflammatory reaction and to progressive valve dysfunction.

机译：瓣膜性心脏病有许多病因。这些范围从先天畸形到传染性和退行性疾病。在临床上，这些会导致严重的问题，要解决这些问题可能需要用人工心脏瓣膜置换瓣膜。罕见的原因是外来物质在瓣膜组织中的沉积，其中包括先天氨基酸代谢必需氨基酸。碱性磷酸酶尿症（一种常染色体隐性遗传）可导致过量的高尿酸积累。这可以表现为皮肤和其他组织（包括心脏瓣膜）中的色素沉着。这种色素的积累会导致炎症反应和进行性瓣膜功能障碍。

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来源
《Journal of cardiac surgery.》 |2006年第2期|共3页
作者
Butany JW; Naseemuddin A; Moshkowitz Y; Nair V;
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正文语种 eng
中图分类外科学;
关键词
Ochronosis; Aortic Valve Stenosis; heart valve effects; Materials; 褐黄病; 主动脉瓣狭窄;

机译：Ochronosis;Aortic Valve Stenosis;heart valve effects;Materials;褐黄病;主动脉瓣狭窄;

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1. Ochronosis and aortic valve stenosis. [J] . Butany JW, Naseemuddin A, Moshkowitz Y, Journal of cardiac surgery. . 2006,第2期

机译：骨质疏松症和主动脉瓣狭窄。
2. The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement [J] . Timothy Fairbairn, Christopher D Steadman, Adam N Mather, Journal of cardiovascular magnetic resonance : . 2012,第Suppla1期

机译：严重主动脉瓣膜置换术后心肌纤维化对心室重构的影响。 CMR研究比较经导管主动脉瓣植入和手术主动脉瓣置换
3. Balloon aortic valvuloplasty under temporary mechanical circulatory support as a bridge to aortic valve replacement in a patient with hemodynamic failure secondary to critical aortic valve stenosis. [J] . Salil Deo, Kevin L Greason, Rajiv Gulati, The heart surgery forum . 2012,第3期

机译：暂时性机械循环支持下的球囊主动脉瓣膜成形术，是继发于严重主动脉瓣狭窄的血流动力学衰竭患者主动脉瓣置换的桥梁。
4. Severe systolic dysfunction is a good predictor of developing acute coronary syndrome in patients with degenerative aortic stenosis. [C] . Pop C., Dan D., Petris A., International Congress on Coronary Artery Disease . 2009

机译：严重的收缩功能障碍是在退行性主动脉狭窄患者中发育急性冠状动脉综合征的良好预测因子。
5. Discovering the link between bicuspid aortic valve and aortic aneurysms: Genetic or hemodynamic? [D] . Habchi, Karam 2015

机译：发现二尖瓣主动脉瓣和主动脉瘤之间的联系：遗传还是血液动力学？
6. The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement [O] . Timothy Fairbairn, Christopher D Steadman, Adam N Mather, 2012

机译：严重主动脉瓣膜置换术后心肌纤维化对心室重构的影响。 CMR研究比较经导管主动脉瓣植入和手术主动脉瓣置换
7. The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement [O] . Timothy Fairbairn, Christopher D Steadman, Adam N Mather, 2012

机译：严重主动脉瓣膜置换术后心肌纤维化对心室重构的影响。 CMR研究比较经导管主动脉瓣植入和手术主动脉瓣置换

Ochronosis and aortic valve stenosis.

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