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首页> 外文期刊>Journal of cardiology >Generator-produced rubidium-82 positron emission tomography myocardial perfusion imaging-From basic aspects to clinical applications
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Generator-produced rubidium-82 positron emission tomography myocardial perfusion imaging-From basic aspects to clinical applications

机译：发生器产生的82 82正电子发射断层扫描术心肌灌注成像-从基本方面到临床应用

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摘要

Cardiovascular disease is the leading cause of death in modern industrialized countries with an aging population. This fact has fueled the need for innovative diagnostic testing intended to improve coronary artery disease (CAD) patient care. Detection of myocardial ischemia using myocardial perfusion imaging (MPI) plays an important role for CAD diagnosis and the prediction of future risk of cardiovascular events. Positron emission tomography (PET) MPI has high diagnostic accuracy and can estimate regional myocardial blood flow (MBF) in patients with CAD. Rubidium-82 (82Rb) is a generator-produced PET myocardial perfusion tracer and has been widely used in North America in clinical practice. 82Rb PET has recently become available in some cardiovascular centers in Europe and Japan. Clinical trials are expected in both regions. 82Rb PET has high diagnostic accuracy and recent data have shown its prognostic value. Thus, 82Rb PET would greatly contribute to CAD patients' care. 82Rb PET can also be used to quantify MBF. This review describes the current status of 82Rb MPI from basic principles to clinical implications. This paper also highlights the recent development of MBF quantification using 82Rb PET.
机译：在人口老龄化的现代工业化国家，心血管疾病是主要的死亡原因。这一事实激发了对旨在改善冠状动脉疾病（CAD）患者护理的创新诊断测试的需求。使用心肌灌注成像（MPI）检测心肌缺血对于CAD诊断和预测心血管事件的未来风险起着重要作用。正电子发射断层扫描（PET）MPI具有很高的诊断准确性，并且可以估计CAD患者的局部心肌血流（MBF）。 id 82（82Rb）是发生器生产的PET心肌灌注示踪剂，已在北美的临床实践中广泛使用。 82Rb PET最近在欧洲和日本的一些心血管中心上市。预计这两个地区都将进行临床试验。 82Rb PET具有很高的诊断准确性，最近的数据显示出其预后价值。因此，82Rb PET将大大有助于CAD患者的护理。 82Rb PET也可用于定量MBF。这篇综述从基本原理到临床意义都描述了82Rb MPI的现状。本文还重点介绍了使用82Rb PET进行MBF定量分析的最新进展。

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