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首页> 外文期刊>Journal of cardiology >Health-related quality of life in Japanese patients with ischemic heart disease: a multicenter cooperative investigation assessed using SF-36
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Health-related quality of life in Japanese patients with ischemic heart disease: a multicenter cooperative investigation assessed using SF-36

机译：日本缺血性心脏病患者的健康相关生活质量：使用SF-36评估的多中心合作研究

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摘要

OBJECTIVES: To investigate the quality of life (QOL) of Japanese patients with ischemic heart disease. METHODS: The QOL data of 753 patients with chronic and stable ischemic heart disease was assessed using SF-36 Japanese version 1.2 and compared with Japanese national norms. Physical (PCS) and Mental Component Summary (MCS) scores were calculated to examine the correlation with patient background. Patients were also asked about subjective symptoms during the QOL investigation. RESULTS: Mean age was 63.6 +/- 7.5 years old and the male/female ratio was 85.7/14.3. About one third (30.7%) of the patients were symptomatic and about half (52.6%) had a history of myocardial infarction. Compared to Japanese national norms, physical functioning, role-physical, social functioning, general health and role-emotional were lower, and body pain, vitality and mental health were higher. PCS was significantly lower and MCS was significantly higher in aged patients than in younger patients (p < 0.0001, p < 0.0001). PCS and MCS were significantly lower in the symptom (+) group than in the symptom (-) group (p = 0.0009, p < 0.0001). PCS decreased as the number of anti-angina medications for the patients increased (p = 0.0002). PCS was significantly lower and MCS was significantly higher in the beta blocker (+) group than in the beta blocker (-) group (p < 0.0001, p < 0.03). Multivariate logistic regression analysis showed that age ( > or = 63 years old), symptom (+), duration of disease (> or = 3 years) and beta blocker (+) influenced the QOL. CONCLUSIONS: The QOL level of patients with ischemic heart disease was found to depend on the clinical condition and treatment, so the optimal treatment for ischemic heart disease must be established to improve QOL.
机译：目的：调查日本缺血性心脏病患者的生活质量（QOL）。方法：使用SF-36日本1.2版评估了753例慢性稳定性缺血性心脏病患者的QOL数据，并与日本国家标准进行了比较。计算身体（PCS）和心理成分摘要（MCS）分数，以检查与患者背景的相关性。在QOL调查期间还询问患者主观症状。结果：平均年龄为63.6 +/- 7.5岁，男女比例为85.7 / 14.3。约三分之一（30.7％）的患者有症状，约一半（52.6％）的患者有心肌梗塞病史。与日本国家规范相比，身体机能，角色-身体，社会功能，总体健康和角色情感较低，身体疼痛，活力和精神健康较高。与年轻患者相比，老年患者的PCS显着降低，MCS显着更高（p <0.0001，p <0.0001）。症状（+）组的PCS和MCS显着低于症状（-）组（p = 0.0009，p <0.0001）。随着患者抗心绞痛药物数量的增加，PCS下降（p = 0.0002）。与β受体阻滞剂（-）组相比，β受体阻滞剂（+）组的PCS显着降低，而MCS显着更高（p <0.0001，p <0.03）。多因素logistic回归分析显示年龄（>或= 63岁），症状（+），疾病持续时间（>或= 3岁）和β受体阻滞剂（+）影响生活质量。结论：缺血性心脏病患者的QOL水平取决于临床情况和治疗，因此必须建立缺血性心脏病的最佳治疗方法以改善QOL。

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