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首页> 外文期刊>Journal of child psychology and psychiatry >Childhood psychopathology in children of women with eating disorders: Understanding risk mechanisms
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Childhood psychopathology in children of women with eating disorders: Understanding risk mechanisms

机译:饮食失调妇女的儿童心理病理学:了解危险机制

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Background Very few studies have investigated psychopathology in children of mothers with eating disorders (ED). We aimed to determine the effect of maternal ED on childhood psychopathology in a large population-based cohort and investigate relevant risk pathways using structural equation modeling (SEM). Methods Data on emotional and behavioral problems at 3 years were obtained prospectively on 8,622 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children of exposed women who self-reported lifetime anorexia nervosa (AN, N = 193) or bulimia nervosa (BN, N = 158) in pregnancy were compared with children of unexposed women (N = 8,271) using linear and logistic regression models. SEM was used to determine best-fitting risk models by child gender. Results There was evidence that girls of AN women were more likely to have emotional, conduct, and hyperactivity disorders [Odds Ratio (OR): 1.7 (95% Confidence Intervals 1.0-3.0); OR: 2.2 (1.2-4.0); OR: 1.8 (1.1-3.1), respectively] and boys of AN women to have emotional disorders compared with unexposed [OR: 2.0(1.2-3.4)]. Girls of women with BN were more likely to show hyperactivity [OR: 1.7 (1.0-3.1)]; and boys to show emotional and conduct disorders compared with unexposed [OR: 2.2 (1.2-3.9); OR: 2.4 (1.4-4.2), respectively]. SEM models showed that pregnancy anxiety and depression mediated the effect of maternal ED on child psychopathology. Conclusions Maternal ED are associated with different childhood psychopathology outcomes in boys and girls. Pregnancy anxiety and depression and active ED symptoms are important mediators of risk and are preventable; the direct effect of maternal lifetime ED was small.
机译:背景很少有研究调查患有进食障碍(ED)的母亲的孩子的心理病理。我们旨在确定以母亲为基础的大型人群中ED对儿童心理病理的影响,并使用结构方程模型(SEM)研究相关的风险途径。方法前瞻性地从雅芳父母与儿童纵向研究(ALSPAC)的8,622名儿童中获得3年时情绪和行为问题的数据。使用线性和逻辑回归模型比较自我报告的终生神经性厌食症(AN,N = 193)或神经性贪食症(BN,N = 158)的暴露妇女的孩子与未暴露妇女的孩子(N = 8,271)。 SEM被用来确定按儿童性别划分的最合适的风险模型。结果有证据表明,AN妇女的女孩更容易出现情绪,行为和多动障碍[几率(OR):1.7(95%的置信区间为1.0-3.0);或:2.2(1.2-4.0); OR:分别为1.8(1.1-3.1)]和AN妇女的男孩与未暴露者相比有情感障碍[OR:2.0(1.2-3.4)]。患有BN的女性女孩更容易出现多动[OR:1.7(1.0-3.1)];与未暴露相比,男孩和男孩表现出情绪和行为障碍[OR:2.2(1.2-3.9);或:2.4(1.4-4.2)]。扫描电镜模型表明,怀孕焦虑和抑郁情绪介导了母体ED对儿童心理病理的影响。结论母体ED与男孩和女孩的不同儿童期心理病理结果相关。怀孕焦虑和抑郁以及活跃的ED症状是重要的危险介质,可以预防。产妇一生ED的直接影响很小。

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