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Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects

机译:光学相干断层扫描在人类受试者口服不同糖类期间的无创血糖监测

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摘要

The potential of OCT applied to noninvasive blood glucose monitoring has attracted significant efforts. In this work we investigated the feasibility of OCT in monitoring blood glucose during oral intake of different sugars in humans. Five groups of experiments were performed, in which different sugars were used. The OCT signal slope (OCTSS) changed with variation of blood glucose concentration (BGC). A good correlation between OCTSS and BGC was observed in these experiments. The averaged correlation coefficients R between OCTSS and BGC are 0.900, 0.836, 0.895 and 0.884, corresponding to oral administration of glucose, fructose, sucrose and mixed sugar, respectively. Our studies demonstrated the capability and accuracy of the OCT system in monitoring BGC noninvasively and it could become a powerful tool in daily blood glucose monitoring for patients. ((c) 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
机译:OCT应用于无创血糖监测的潜力吸引了巨大的努力。在这项工作中,我们调查了OCT在人类口服不同糖类期间监测血糖的可行性。进行了五组实验,其中使用了不同的糖。 OCT信号斜率(OCTSS)随血糖浓度(BGC)的变化而变化。在这些实验中,OCTSS和BGC之间存在良好的相关性。 OCTSS和BGC之间的平均相关系数R为0.900、0.836、0.895和0.884,分别对应于口服葡萄糖,果糖,蔗糖和混合糖。我们的研究表明,OCT系统无创监测BGC的能力和准确性,可以成为患者日常血糖监测的有力工具。 ((c)2013 WILEY-VCH Verlag GmbH&Co.KGaA,Weinheim)

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