...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism >Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease.
【24h】

Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease.

机译：通过闭塞性血管疾病中脑血管储备和氧提取分数的血流动力学损害的鉴定。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cerebrovascular reserve (CVR) and oxygen extraction fraction (OEF) are used to identify hemodynamic compromise in symptomatic patients with carotid occlusive vascular disease, but evidence suggests that they are not equivalent. The authors studied the relationship between CVR and OEF to evaluate their equivalence and stages of hemodynamic compromise. Symptomatic patients (N = 12) with carotid occlusion were studied by stable xenon-computed tomography CBF after intravenous acetazolamide administration for CVR, followed within 24 hours by positron emission tomography (PET) for OEF. Middle cerebral artery territories were analyzed by hemisphere and level. Hemispheric subcortical white matter infarctions were graded with magnetic resonance imaging. Both hemispheric and level analysis of CVR and OEF showed a significant (P = 0.001), negative linear relationship [CVR (%) = -1.5 (OEF) + 83.4, (r = -0.57, P = 0.001, n = 24]. However, 37.5% of the hemispheres showed compromised CVR but normal OEF and were associated (P = 0.019) with subcortical white matter infarction. CMRO2 was elevated in stage II hemodynamic compromise (CVR < 10%, OEF > 50%). CVR and OEF showed a significant negative linear relationship in stage II hemodynamic compromise but revealed hemispheres in hemodynamic compromise by CVR but normal OEF that were associated with subcortical white matter infarction.
机译：脑血管储备（CVR）和氧提取分数（OEF）用于确定患有颈动脉闭塞性血管疾病的有症状患者的血液动力学损害，但证据表明它们并不等效。作者研究了CVR和OEF之间的关系，以评估它们的等效性和血液动力学损害的阶段。对有症状的颈动脉闭塞患者（N = 12）在静脉内给予乙酰唑胺用于CVR后，通过稳定的氙气X线断层扫描CBF进行研究，然后在24小时内对OEF进行正电子发射断层扫描（PET）。通过半球和水平分析大脑中动脉区域。用磁共振成像对半球皮质下白质梗死进行分级。 CVR和OEF的半球和水平分析均显示出显着的（P = 0.001）负线性关系[CVR（％）= -1.5（OEF）+ 83.4，（r = -0.57，P = 0.001，n = 24]。然而，有37.5％的半球显示CVR受损但OEF正常，并与皮层下白质梗死相关（P = 0.019）; CMRO2在II期血流动力学损害中升高（CVR <10％，OEF> 50％）。在II期血液动力学损害中显示出显着的负线性关系，但在CVR但正常OEF的血液动力学损害中发现半球与皮质下白质梗死有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号