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Genetics: does it play a role in tendinopathy? Sport Medicine

机译:遗传学:它在肌腱病中起作用吗?运动医学

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摘要

Chronic tendinopathy is frequent in both elite and recreational athletes. Sedentary subjects may also develop tendinopathy in the absence of any history of increased physical activity.Most research on tendon injuries has focused on a description of the condition and its management, rather than on the underlying cellular and molecular mechanisms of causation.1 Although several such mechanisms have been implicated, the causes of tendon problems in athletes are poorly understood.1 "Differential strain," "stress shielding," joint position, and even underuse have all been advanced as alternative biomechanical explanations to the classical overuse model for the pathogenesis of tendinopathy.
机译:慢性肌腱病在精英运动员和休闲运动员中都很常见。久坐的受试者也可能在没有任何增加运动量的病史的情况下发展为肌腱病。关于肌腱损伤的大多数研究都集中在对病情及其治疗的描述上,而不是在病因的潜在细胞和分子机制上。1涉及机制,对运动员肌腱问题的原因了解甚少。1“差异应变”,“应力屏蔽”,关节位置乃至使用不足均已被提出,以作为经典过度使用模型的替代生物力学解释,以解释这种疾病的发病机理。肌腱病。

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