• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical investigation >Assessing health-related quality of life in cancer trials
【24h】

Assessing health-related quality of life in cancer trials

机译：在癌症试验中评估与健康相关的生活质量

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In cancer clinical trials, the evaluation of treatment options is often dominated by patient survival. However, treatment improvements have permitted survival to be measured in years rather than months for many cancer patients. This trend is likely to persist and the quality of survival as reported by patients will become an increasingly important end point. Additionally, when new cancer therapies show small survival gains, the quality of this survival period from the patient perspective should be assessed in order to adequately evaluate the new agent and to inform clinicians and patients about tradeoffs in the form of treatment-related side effects. This article describes the rationale for measuring health-related quality of life outcomes in cancer trials, and key design and methodological considerations in clinical trial settings.
机译：在癌症临床试验中，对治疗方案的评估通常取决于患者的生存率。但是，对于许多癌症患者来说，治疗方法的改进使人们可以用数年而不是数月的时间来衡量生存率。这种趋势可能会持续下去，患者报告的生存质量将成为越来越重要的终点。此外，当新的癌症疗法显示出较小的生存期增加时，应从患者角度评估该生存期的质量，以便充分评估新药并以治疗相关副作用的形式告知临床医生和患者有关权衡的方法。本文介绍了在癌症试验中测量与健康相关的生活质量的基本原理，以及在临床试验环境中进行关键设计和方法学考虑。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号